Thioridazine (Mellaril, Novoridazine, Thioril)
Generic name: Mellaril
Brand names: Mellaril, Novoridazine, Thioril
What is Thioridazine (Mellaril, Novoridazine, Thioril)?
Thioridazine is in a class of remedies called phenothiazines. It works by changing the actions of chemicals in the brain.
Thioridazine is taken to heal psychotic disorders, such as schizophrenia. Thioridazine is generally reserved for people who do not respond to other pharmaceuticals or who cannot take other remedies due to side effects.
Thioridazine may also be taken for goal other than those listed in this medication guide.
What is the most important information I should know about thioridazine?
Do not take thioridazine if you have any of the following conditions or a history of these conditions:
- heart disease;
- an irregular heartbeat or a history of irregular heartbeats;
- a history of prolonged QT intervals;
- a family history of congenital long QT clues;
- or other heartbeat disturbances.
These conditions may increase the risk of irregular heartbeats, heart attack, and death while taking thioridazine.
Do not use thioridazine with any of the following specifics:
- psychiatric pharmaceuticals such as fluoxetine (Prozac), paroxetine (Paxil, Paxil CR), and fluvoxamine (Luvox);
- or blood pressure pills such as pindolol (Visken) or propranolol (Inderal, Inderal LA, others).
Taken with any of these pharmaceuticals, thioridazine may cause irregular heartbeats that could lead to death. This is not a complete list of specifics that may interact with thioridazine and cause heart problems. Talk to your doctor or pharmacist before taking any other prescription or over-the-counter medications. Thioridazine may interact with other specifics that cause drowsiness, including alcohol, antidepressants, antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants.
Dangerous sedation, dizziness, or drowsiness may occur if thioridazine is taken with alcohol or any of these medications. Inform your health care provider before taking thioridazine in combination with alcohol or any other medicine. Take caution when driving, operating machinery, or performing other hazardous activities. Thioridazine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
Call your health care provider immediately if you have uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs; fever; muscle rigidity; sweating; irregular pulse; or fast or irregular heartbeats.
What should I inform my pediatrician before taking thioridazine?
Before taking thioridazine, report to your pediatrician if you have:
- bone marrow disease
- Parkinson’s sickness
- an enlarged prostate or difficulty urinating
- liver disease
- kidney sickness
You may not be able to take thioridazine, or you may demand a dosage adjustment or special monitoring during treatment if you have any of the disorders listed above.
It is not known whether thioridazine will harm an unborn baby. Do not use thioridazine without first talking to your doctor if you are pregnant or could become pregnant during medication. It is not known whether thioridazine passes into breast milk. Do not take thioridazine without first talking to your doctor if you are breast-feeding a baby. If you are over 60 years of age, you may be more likely to experience side effects from thioridazine. Your physician may prescribe a lower dose of this cure or you may demand special monitoring during medication.
How should I take thioridazine?
Use thioridazine exactly as directed by your pediatrician. If you do not understand these instructions directions, ask your health care provider to explain them to you.
Your pediatrician may want to monitor your heartbeats and obtain a blood sample before starting and periodically during medication with thioridazine.
Take each dose with a full drink of water.
Thioridazine can be used with or without food.
Do not stop taking thioridazine without first talking to your pediatrician. It may be several weeks before you begin to feel better, and you may need continuous medication for quite some time. Keep thioridazine at room temperature away from moisture and heat.
What should I avoid while taking thioridazine?
Use caution when driving, operating machinery, or performing other hazardous activities. Thioridazine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
Thioridazine may interact with other remedies that cause drowsiness, including alcohol, antidepressants, antihistamines, pain relievers, anxiety medicines, seizure pharmaceuticals, and muscle relaxants.
Thioridazine side effects
If you experience any of the following serious side effects, stop taking thioridazine contact your pediatrician immediately:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
- uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs
- muscle rigidity
- muscle spasms of the face or neck
- irregular pulse
- fast or irregular heartbeats
- severe restlessness or tremor
- severe drowsiness
- blurred vision
- dizziness or fainting
Other, less serious side effects may be more likely to occur. Continue to take thioridazine and inform your nurse if you experience:
- dry mouth, stuffy nose
- mild restlessness, drowsiness, or tremor
- decreased sex drive
- increased appetite
- difficult urination or dark urine
- menstrual irregularities or swollen breasts
Side effects other than those listed here may also occur. Inform your nurse about any side effect that seems unusual or that is especially bothersome.
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