Antidepressants

Elavil is a popular medicine that is known as a tricyclic antidepressant. It diminishes clues of bulimia (an eating disorder), pathological weeping and laughing (associated with multiple sclerosis), migraine headaches and mental depression.

Remeron is a popular drug that has been labeled as a tetracyclic antidepressant. It is given to help relieve symptoms of depression such as loss of interest in activities that you would normally enjoy doing, sleeping problems, loss of appetite, anxiety and feeling low. Your doctor may prescribe this remedy for other purposes.

Tofranil is a popular antidepressant medicine that is known as a tetracyclic antidepressant. It is used to fight against major depression, obsessive-compulsive disorder, panic disorder, bulimia, enuresis (inability to control urination) and attention deficit disorder in children.

Since Kuhn’s paper on imipramine, it has been believed that antidepressants are most effective in severe depression. Many people, who are sceptical of their widespread use for milder cases, maintain that antidepressants are nevertheless effective and necessary in severe depression. It has also been suggested that the reason some studies find little difference between antidepressants and placebo is because they are conducted with people with mild depression, who dilute the antidepressant effect (National Institute for Clinical Excellence 2004).

The monoamine theory of depression is important because it provides a model for the idea that antidepressant drugs act on the biological basis of depressive symptoms. It forms the basis for the modern idea that depression arises from a chemical imbalance.

Evidence about serotonin and noradrenalin levels in people with depression is inconsistent and confusing and most studies fail to control for the effects of potential confounders, such as previous drug treatment. Overall, there is little evidence to suggest that there is a characteristic abnormality in either of these systems that is associated with depression. Depression rating scales contain items that are not specific to depression, including sleeping difficulties, anxiety, agitation and somatic complaints.

Aventyl is a popular drug that belongs to a tricyclic antidepressant. It diminishes syndromes of depression or chronic pain. Don’t stop treatment with Aventyl earlier than it was prescribed by your doctor even if you notice improvements of your condition.

Sinequan is a popular medication that is known as a tetracyclic antidepressant. It prescribed for the treatment of psychotic depressive disorders, depression, posttraumatic stress disorder (PTSD) and anxiety, including clues of fibromyalgia and chronic pain. Sinequan is not approved for use in children under 12.

The other drug tested around this time, which came to be regarded as an antidepressant, was imipramine. Unlike the tuberculostatic drugs, imipramine is not a stimulant.

Early formulations of the monoamine theory of depression cited two strands of evidence. One was the effects of antidepressant drugs and the other was the effects of reserpine.

Lexapro is a popular antidepressant medication that is known as selective serotonin reuptake inhibitor (SSRI). It decreases syndromes of major anxiety and depression. Your doctor may prescribe this remedy for other purposes.

Comparisons between so-called antidepressant drugs and other sorts of drugs do not indicate that antidepressants have a specific effect on depression. Many other drugs show superior effects to placebo or equal effects to antidepressants in randomised trials, as shown in Table Randomised trials of other drugs for depression.

Fluvoxamine belongs to an antidepressant group of medicines called selective serotonin reuptake inhibitors (SSRIs). This remedy affects chemicals in the brain that may become unbalanced and cause obsessive-compulsive symptoms.

The current recommendation is that antidepressants should be continued for 4-6 months after the resolution of an acute episode of depression. This recommendation probably originates with Kuhn’s advice but subsequently several long-term studies appeared to show that people are more likely to relapse after stopping antidepressants compared to if they continue to take them.

Subsequent accounts reveal the extent of cooperation between psychiatric researchers and pharmaceutical company personnel in the development of antidepressants. Company scientists were involved in providing new compounds for psychiatrists to try and psychiatrists sometimes suggested leads for companies to follow. Nathan Kline subsequently claimed that the industry was sceptical about the market for antidepressants, and was only persuaded to collaborate in research by his own remonstrations.

Pamelor is a popular medicine that is known as tricyclic antidepressant. It lessens variety of conditions such as mental/mood disorders, chronic hives, attention deficit hyperactivity disorder in children, depression, bedwetting and premenstrual depression.

The evidence suggests that use of the term ‘antidepressant’ quickly caught on. By 1959 the term was being used routinely in over 100 papers.