Last updated on April 15th, 2024


Reglan (Metoclopramide) is a prescription medication frequently used to treat digestive problems.
By promoting the movement of stomach contents into the intestines, metoclopramide helps to lessen GERD symptoms, including heartburn and regurgitation.

It is frequently administered by specific medical procedures, chemotherapy, or surgeries to treat nausea and vomiting.

The condition known as delayed gastric emptying (gastroparesis), in which the stomach takes too long to empty its contents, can be treated with metoclopramide by strengthening the contractions of the stomach and intestines.

Metoclopramide tightens the muscles in the upper digestive tract to facilitate the faster movement of food and stomach contents through the digestive system.

Reglan may not be appropriate for everyone and can have adverse effects. Therefore, it’s imperative to use it under a doctor’s supervision. Prolonged usage ought to be circumvented as it has the potential to cause severe movement disorders called tardive dyskinesia.

If you are prescribed Reglan or metoclopramide, it is crucial to follow your doctor’s instructions, tell them about any other medications you take, and report any odd or persistent adverse effects.

How it Works

Reglan blocks serotonin and dopamine receptors. The medication reduces hiccups, has an antiemetic effect, and regulates how the gastrointestinal tract functions. The digestive system’s tone and motor activity are extended, but the stomach’s secretion remains unchanged. There are signs that the medication aids in the healing of duodenal and stomach ulcers.

Reglan therapy should not be stopped before your doctor has ordered it, even if your problem seems to be getting better. If you stop taking the drug too soon, it could make things worse.

Until you know how this drug affects you, take caution when using machinery, driving, climbing, or performing other risky jobs. Avoid consuming alcohol. Before administering Reglan to a child, always contact a medic.

After some research, an inconclusive recommendation was made for the use of metoclopramide for infants with reflux. The populations, dosing schedules, and results of the 12 studies that satisfied the review criteria varied significantly. The currently available evidence does not support either significant benefit or harm associated with metoclopramide. The majority of these studies did not report any adverse effects. Dystonic reactions, oculogyric crises, irritability, sleepiness, emesis, and apnea were among the four occurrences that were reported.

When to Take

As an antiemetic, the medication helps with nausea and vomiting brought on by anesthesia, nutrition problems, radiation therapy, medication side effects (such as foxglove, cytostatic drugs, compounds that suppress cell division, antibiotics, etc.), etc. It helps treat vestibular genesis vomiting, which is brought on by motion sickness. The medication is also used in the complex treatment of gastritis, dyskinesia (abrupt loss of movement) of the abdominal cavity, postoperative paresis, the gut, flatulence, and other conditions in gastroenterology practice.

Increased stomach and intestinal tone, faster pyloric and gastric emptying, and decreased hyperacid stasis are associated with positive effects. Evidence exists that the medication is beneficial in treating dyspepsia, or frequent vomiting and nausea, in individuals with severe cardiac conditions (myocardial infarction, heart failure) and vomiting during pregnancy.

How to Take

  Dosage Administration
Adults 10 mg (1 tablet) orally or 1 ampoule (2 ml = 10 mg) Before meals intramuscularly or intravenously
Children over 6 years 1/2 – 1 tablet Before meals

Reglan is administered parenterally (intramuscularly or intravenously) in severe instances, as well as orally.
Try to take the dose as soon as possible if you forget to take it. Take just one dose if it’s time for your next one. The dosage doesn’t need to be doubled.

Any medication used in excess might have detrimental effects on your health. Get in touch with your healthcare provider right away if you suspect an overdose.

Adverse Effects

Generally, Reglan is well tolerated. There may be uncommon instances of extrapyramidal problems, such as jitteriness and disruption in movement coordination with reduced volume. Metoclopramide’s antagonistic action on the brain’s dopamine receptors plays a significant part in the process underlying these side effects. Caffeine is administered parenterally to eliminate these symptoms. This medicine is given cautiously to children under the age of 14. Tinnitus, sleepiness, and dry mouth are possible side effects of the medication. Reglan is administered after meals to lessen these effects.

Injecting Reglan may interfere with one’s ability to operate a vehicle and carry out tasks requiring close concentration.

There might be other adverse effects not included in this list. Let your doctors know about all the side effects you encounter.


A firmly closed container should be used to keep Reglan at room temperature. It should be kept out of light, dampness, and direct heat. It should not be kept next to a sink or in the restroom. Ensure children cannot get Reglan, and keep it away from animals.

This medication may be prescribed by your doctor for different reasons. If you would like additional information on this medication, contact your doctor.

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