Reglan (Metoclopramide)

Last updated on February 16th, 2024

Generic name: Metoclopramide

Brand names: Reglan, Metoclopramide Hydrochloride, Raglan, Tserukal, Perinorm, Klometol, Bimaral, Komportan, Gastrobids, Imperal, Maksolon, Regastrol, Rimetin, Terperan, Viskal, Klopan, Emetizan, alloys, Makseran, Metoklol, Moriperan, Nauzifar, Paspertin, Peraprin, Plast, Pramin, Primperan, Primperil, Reliverin

What Is Reglan (Metoclopramide)?

Reglan is a brand name for the medication metoclopramide. It is a prescription drug that is commonly used to treat gastrointestinal issues such as:

  1. Gastroesophageal Reflux Disease (GERD): Metoclopramide helps to reduce symptoms of GERD, such as heartburn and regurgitation, by promoting the movement of the stomach contents into the intestines.
  2. Nausea and Vomiting: It is often prescribed to relieve nausea and vomiting caused by conditions such as chemotherapy, surgery, or specific medical procedures.
  3. Delayed Gastric Emptying: Metoclopramide can enhance the contractions of the stomach and intestines, addressing issues of delayed gastric emptying (gastroparesis), which is a condition where the stomach takes too long to empty its contents.

Metoclopramide works by increasing the muscle contractions in the upper digestive tract, which helps to speed up the movement of food and stomach contents through the digestive system.

It’s essential to use Reglan under the supervision of a healthcare professional, as it can have side effects and may not be suitable for everyone. Long-term use should be avoided, as it may lead to severe movement disorders known as tardive dyskinesia.

If you are prescribed Reglan or metoclopramide, it’s essential to follow your healthcare provider’s instructions, inform them of any other medications you are taking, and report any unusual or persistent side effects. As with any medication, it’s essential to use it only as directed by your healthcare provider.


Pharmacological Effects

This medicine is a specific blocker of dopamine receptors and serotonin receptors. The medicine has an antiemetic effect, calms hiccups, and has a regulating effect on the function of the gastrointestinal tract. The tone and motor activity of the digestive system extends. Secretion of the stomach does not change. There are indications that the medicine promotes the healing of ulcers of the stomach and duodenum.

Your doctor may prescribe this remedy for other purposes. Contact your physician if you need to learn more information about this drug.

Don’t stop treatment with Reglan earlier than it was prescribed by your doctor, even if you notice improvements in your condition. Stopping the medication too early may worsen your condition. Be careful about doing dangerous tasks, driving, operating machinery, or climbing until you are aware of how this drug affects you. Don’t drink alcohol. Always contact a medic before giving Reglan to a child.


The medicine is an antiemetic in nausea and vomiting associated with anesthesia, diet violations, radiation therapy, side effects of medicines (foxglove, cytostatic agents/substances that suppress cell division/antibiotics, etc.), etc. It helps to treat vomiting of vestibular genesis (caused by motion sickness). In gastroenterological practice, the medicine is also used in the complex treatment of gastric ulcer and duodenal ulcer, gastritis, dyskinesia (violation of the mobility) of the abdominal cavity, postoperative paresis, the intestine, flatulence, and other diseases.

The beneficial effects are associated with increased tone of the stomach and intestines, accelerated gastric emptying and pyloric, and decreased hyperacid stasis. There is evidence of the effectiveness of the medicine in the treatment of dyspepsia (repeated vomiting, nausea) in patients with severe cardiac (myocardial infarction, heart failure) and vomiting during pregnancy.


Note: This remedy was prescribed to you only. Don’t share this medication with others. Follow your doctor’s recommendations strictly. Don’t take more or longer than your doctor recommended.

Reglan is taken orally and, in severe cases, parenterally (intramuscularly or intravenously). Adults usually take 10 mg (1 tablet) orally thrice daily (before meals). It is injected intramuscularly (or intravenously) 1 ampoule (2 ml = 10 mg) 1-3 times daily. Children are prescribed in smaller doses according to age (children older than six years 1/2-1 tablet three times a day).

Side Effects

Reglan is usually well tolerated. In rare cases, there are possible extrapyramidal disorders, such as disturbance of coordination of movements with decreased volume and jitter. The main role in the mechanism of these adverse effects is the antagonistic action of metoclopramide on dopamine receptors of the brain. To remove these phenomena, caffeine is injected parenterally. Children under the age of 14 are prescribed with caution. While using the drug, you may notice dry mouth, tinnitus, and drowsiness. To reduce these effects, medication is prescribed after meals.

This list of side effects may not be complete; others may occur. Inform your medical practitioners about all the side effects you experience.


Taking Reglan by injection may disrupt the ability to drive vehicles and perform work that requires particular attention.


This list of interactions may not be complete. Provide your medical practitioner with an entire list of medicines, herbs, dietary supplements, or non-prescription drugs you take. Moreover, tell them whether you drink alcohol, use illegal drugs, or smoke.

What Should I Do If I Miss the Dose?

If you miss the dose, try to take it as soon as possible. If it is time for your next dose, take only one dose. You don’t have to double the dose.


Taking any medicine in large doses can have severe consequences for your health. If you feel an overdose, contact your healthcare professional instantly.


Reglan should be stored at room temperature in a tightly closed container. Protect from moisture, direct heat, and light. Do not store it in the bathroom or near a sink. Keep Reglan out of the reach of children and away from animals.

Warning: Before taking the drug, you need to consult your doctor. The information contained in this article is not intended to cover all possible precautions, drug interactions, adverse effects, directions, uses, allergic reactions, or warnings.

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