Last updated on April 12th, 2024


The medication Hyzaar is used to treat hypertension. This medication is a mixture of two drugs: a thiazide “water pill”/diuretic and an angiotensin receptor blocker. Blood vessels enlarge and relax when using Hyzaar. By increasing the volume of urine produced, the thiazide diuretic reduces the amount of extra water and salt in your body. Maintaining blood pressure control can help prevent kidney issues, heart attacks, and strokes.

Your doctor may prescribe this medication for other reasons. If you would like additional information on this medication, contact your doctor.

Even if your condition seems to be improving, don’t stop taking Hyzaar earlier than your doctor has instructed. If you stop taking the drug too soon, it could make things worse. Until you know how this drug affects you, take caution when operating machinery, driving, climbing, or performing other risky actions. Avoid consuming alcohol. Never provide Hyzaar to a child without first consulting a physician.

How Should I Use Hyzaar?

Note: Don’t give this medication to anyone else. Please take it as prescribed by your doctor, neither more nor less.

Hyzaar is administered orally with food, milk, or an antacid to avoid stomach upset. Unless your doctor instructs you otherwise, you may also take it with a full glass of water. Avoid lying down for half an hour after taking this medication. Administer the dosages regularly.

Excessive or Missed Dose

Any medication used in excess might have adverse effects on your health. Get in touch with your healthcare provider right away if you suspect an overdose.

If you forget to take a dose, take it as soon as possible. Never take two doses at once if your next dose is almost due. Take one dosage at a time.

Which Medical Issues or Symptoms Should I Notify a Doctor About Before Using Hyzaar?

Consult a physician if any of the following apply to you or have previously affected you:

  • allergies or asthma;
  • lupus;
  • an allergy to sulfa medications;
  • liver or kidney problems;
  • gout;
  • low or high blood potassium levels;
  • congestive cardiac dysfunction;
  • diabetes.

Adverse Effects

If you have any of the following severe side effects, get in touch with your doctor right away:

  • allergy symptoms such as a skin rash, lips, tongue, and facial swelling, hives, itching, and breathing difficulties;
  • reduced or absent urination, as opposed to increasing urination;
  • quick increase in weight;
  • fainting and swelling;
  • pale complexion, dizziness, pounding or rapid heartbeat, and elevated heart rate;
  • confusion;
  • sleepiness, easy bruising or bleeding, dry mouth, increased thirst, jaundice (yellowing of the skin or eyes), convulsions, or a restless feeling.

Less severe adverse effects:

  • skin rash;
  • sore throat;
  • dry cough;
  • backache;
  • nausea and dizziness;
  • stuffy or runny nose.

Other adverse effects could occur; this is not an exhaustive list. Tell your doctors about all the side effects you encounter.


Try not to get too hot or dehydrated when exercising in hot weather. Speak with your doctor to determine how much liquids you should consume daily. Unless advised otherwise by your doctor, stay away from potassium supplements and salt replacements while undergoing therapy. If taken during the latter six months of pregnancy, this medication has the potential to damage or even kill the fetus. See your doctor right away if you become pregnant or suspect you might be pregnant. Avoid abrupt standing or sitting up, particularly if you are an elderly patient. Regularly check your blood pressure. Tests for your renal function can also be necessary.

This page does not aim to cover all the information about Hyzaar, including safety measures, medication interactions, side effects, usage, recommendations, allergic reactions, or warnings.

How to Store

Hyzaar needs to be kept in a firmly closed container at room temperature. Keep out of the light, heat, and moisture. Store away from sinks and bathrooms. Hyzaar should be kept out of children’s reach and away from animals.


Is it safe for anyone to take Hyzaar?

Not everyone can safely use Hyzaar. You must present your healthcare practitioner with all of your medical history, including any prior illnesses you may have had, such as diabetes, liver disease, renal disease, or electrolyte abnormalities. Furthermore, disclose to your healthcare provider whether you are nursing a baby, intend to become pregnant, or are currently pregnant, as Hyzaar may not be appropriate during these times.

How much time does it take for Hyzaar to start working?

After taking the first dose, Hyzaar may begin to lower your blood pressure within a few hours, but it may take up to two weeks to feel the drug’s full effects. Even if Hyzaar does not start working immediately, taking medication as directed is crucial. Talk to your healthcare practitioner about any worries you may have regarding the efficacy of Hyzaar.

Can an allergic response occur from Hyzaar?

Yes, some people may experience allergic reactions when using Hyzaar. An allergic reaction may manifest as a rash, itching, facial, lip, tongue, or throat swelling, extreme dizziness, or difficulty breathing. See a doctor immediately if you get these symptoms after taking Hyzaar. Hyzaar allergies can be severe and need to be treated right away. Do not take Hyzaar, and notify your healthcare practitioner if you have a known allergy to any of its ingredients.

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