Azulfidine (Sulfasalazine)

Azulfidine
4.522 ratingsReviews
Generic:
Sulfasalazine
Indications:
ulcerative colitis
Analogs:
Salazopyrin Mesalamine Balsalazide Olsalazine Methotrexate Hydroxychloroquine Leflunomide Asacol Pentasa Lialda Plaquenil Arava Colazal Dipentum
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Azulfidine 500 mg

Quantity Price per tablet You save Total price
60 $2.07 - $124.00
90 $1.86 $19.00 $167.00
120 $1.75 $38.00 $210.00
180 $1.61 $83.00 $289.00
270 $1.54 $143.00 $415.00

Manufacturers

AlphapharmIpca Laboratories Ltd.Pfizer

Payment & Shipping

Package Example

Your order is securely packed and usually ships within 24 hours. Below is what a standard package looks like.

It is about the size of a regular letter (9.4x4.3x0.3 inches) and shows no details about what is inside.

Front View
Front View
Side View
Side View
Back View
Back View
Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over $300.00Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00Estimated delivery to the U.S.: 14-21 days
EMSUSPS
Payment Methods
VisaMastercardAmerican ExpressDiscoverBitcoin, USDTApple PayGoogle PayPayPal

Discount Coupons

  • Independence Day - July 4, 2026 10% JULY410
  • Labor Day - September 7, 2026 7% LABOR07
  • Thanksgiving - November 26, 2026 9% THANKS09

Brand Names

Also known as (by country):
CountryBrand Names
United Kingdom
Salazopyrin Salazopyrin EN-Tabs
Canada
Salazopyrin
Australia
Pyralin EN Salazopyrin
New Zealand
Salazopyrin

FAQ

Sulfasalazine is a prescription medicine when purchased from local U.S. pharmacies. Our store policy allows customers to order these 500 mg sulfasalazine tablets without submitting a prescription, and the product can be sent by mail. A clinician should still guide treatment and monitoring.

Take the tablet with a full glass of water, sitting upright, and consider using an approved pill-swallowing technique. Do not crush, chew, or split it unless a pharmacist or prescriber confirms that the specific tablet you receive can be altered; the available product data do not establish that this formulation may be crushed or split.

They may differ. The supplied product is identified by its active ingredient, sulfasalazine, 500 mg strength, and tablet form, but the exact manufacturer and inactive ingredients are not confirmed in advance. Check the ingredient list on the package received, especially if you have an allergy or sensitivity to a dye, lactose, gluten, or another excipient.

Sulfasalazine is an aminosalicylate anti-inflammatory medicine used for ulcerative colitis, including treatment of mild to moderate disease and helping maintain remission between attacks. It is also an established disease-modifying treatment for rheumatoid arthritis. The appropriate use depends on the condition, disease severity, and monitoring plan.

Description

General Information

Azulfidine is a medication that has anti-inflammatory and anti-microbial qualities. It is a mixture of 5-aminosalicylic acid and sulfapiridin. The medication is absorbed in small amounts from the colon's lumen and then evenly distributed within the connective tissue. Because Azulfidine is more readily absorbed (up to 30% of the dose), it primarily has a broad anti-inflammatory effect.

According to the National Library of Medicine, Azulfidine is prescribed for the following conditions:

  1. Rheumatoid arthritis.
  2. Polyarticular Juvenile Idiopathic Arthritis.
  3. Ulcerative colitis.

There are also non-FDA approved (off-label) indications:

  • Ankylosing Spondylitis;
  • Crohn's Disease;
  • Psoriatic Arthritis.

See your physician before using the medication.

How to Take

Azulfidine is given with 240-250 ml of drinking water, preferably before meals.

azulfidina-sulfasalazina-500mg-60grageas

Side Effects and Contraindications

Side effects frequently occur when the medication builds up a high concentration in the blood plasma. Patients with delayed occurrence of sulfapiridin acetylation rate may experience such a condition. Itchy skin, fever, headaches, gastrointestinal tract issues, and erythema are common adverse effects of the medication.

Restrictions

  • hypersensitivity to the medication's ingredients;
  • severe liver and kidney conditions;
  • up to two years of age.

Period of Pregnancy and Nursing

Pregnancy-related use of Azulfidine is permitted, but only in extreme cases. Expectant mothers are advised to select the lowest effective dosage. Breastfeeding is discontinued if medication is required because it is well excreted in breast milk.

Interactions

Digoxin and folic acid are less absorbed when taking Azulfidine, which strengthens the anticoagulant agents.

Please keep Azulfidine at a temperature of no more than 25°C in a dark place.

 

Medically reviewed by
John Buducci
Pharmacology Expert
Updated August 11, 2026

Customer questions

Asked by Maria Hernandez, San Antonio, United States

I just received my tablets. Where should I look for the lot number and expiration date?

Answered by Support team

Check the medicine container or blister packaging and its outer package for the lot number and expiration date. Keep that information with the product, and do not use tablets if the expiration date is missing or has passed.

Asked by Daniel Kim, San Francisco, United States

Before I order, can you tell me how much shelf life the tablets will have left?

Answered by Support team

We cannot promise a specific remaining shelf life in advance. The exact expiration date is printed on the medicine packaging you receive; please check it when the order arrives.

Asked by Michael Thompson, Detroit, United States

I live in Detroit and am concerned about the tablets being in transit. Is this type of medicine suitable for ordinary transportation?

Answered by Support team

Tablets can normally travel through the mail when appropriately packed and kept in their protective container. Store them at 68°F to 77°F, with permitted excursions from 59°F to 86°F, and keep the container tightly closed and away from moisture. On arrival, check that the package and tablets are intact before use.

Asked by Olivia Johnson, Houston, United States

How many 500 mg tablets can I choose from before placing my order?

Answered by Support team

The available package quantities are 60, 90, 120, 180, and 270 tablets. Each tablet contains 500 mg of sulfasalazine.

Asked by James Walker, Jacksonville, United States

I'm starting sulfasalazine soon. Which side effects should make me seek medical help instead of waiting them out?

Answered by Support team
Medical reviewed by Mildred Torres

Nausea, stomach upset, headache, and dizziness can occur, but seek prompt medical attention for a rash with fever, mouth sores, sore throat, unusual bruising or bleeding, yellowing of the skin or eyes, severe fatigue, or trouble breathing. These can signal a serious blood, liver, or hypersensitivity reaction.

Product specifications

Active ingredientSulfasalazine
Drug classAminosalicylate anti-inflammatory
Dosage formTablet
Available strengths500 mg
RouteOral
StorageStore at 68°F to 77°F; excursions permitted from 59°F to 86°F. Keep the container tightly closed and away from moisture.
ATC codeA07EC01

Regulatory information

United States: medicine status
Registration statusAzulfidine 500 mg tablets (sulfasalazine) are an FDA-approved prescription drug product in the United States under NDA 007892.
Prescription statusAzulfidine is available by prescription only in the United States.
Official prescribing informationThe current FDA-required prescribing information, including indications, contraindications, warnings, dosing, and adverse reactions, is available through DailyMed.Safety monitoringSuspected serious adverse events and product-quality problems may be reported to the FDA MedWatch program.

More information