Hyzaar (Losartan-Hydrochlorothiazide)

Hyzaar
4.85 ratingsReviews
Generic:
Losartan-Hydrochlorothiazide
Indications:
hypertension stroke
Analogs:
Cozaar Diovan Hct Avalide Atacand Hct Micardis Hct Benicar Hct Zestoretic Vaseretic Lotensin Hct Amlodipine Chlorthalidone
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Hyzaar 12.5mg+12.5mg

Quantity Price per tablet You save Total price
30 C$1.59 - C$47.60
60 C$1.28 C$18.20 C$77.00
90 C$1.29 C$26.60 C$116.20
120 C$1.16 C$51.80 C$138.60
180 C$1.07 C$92.40 C$193.20
360 C$0.90 C$246.40 C$324.80

Hyzaar 25mg+12.5mg

Quantity Price per tablet You save Total price
30 C$0.93 - C$28.00
60 C$0.86 C$4.20 C$51.80
90 C$0.76 C$15.40 C$68.60
120 C$0.72 C$25.20 C$86.80

Hyzaar 50mg+12.5mg

Quantity Price per tablet You save Total price
30 C$3.36 - C$100.80
60 C$2.87 C$29.40 C$172.20
90 C$2.71 C$58.80 C$243.60
120 C$2.63 C$88.20 C$315.00
180 C$2.56 C$144.20 C$460.60
270 C$2.51 C$228.20 C$679.00
360 C$2.49 C$312.20 C$897.40

Manufacturers

ApotexBiogaranCipla LimitedOrganonOrganon CanadaOrganon FranceOrganon HealthcareOrganon ItaliaOrganon SaludUnichem Laboratories Ltd.

Payment & Shipping

Package Example

Your order is securely packed and usually ships within 24 hours. Here is what a typical parcel looks like.

It is about the size of a regular letter (24x11x0.7 cm) and does not show any details of what is inside.

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Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over C$420.00Estimated delivery to Canada: 4-7 days
Standard Free for orders over C$280.00Estimated delivery to Canada: 14-21 days
EMSCanada Post
Payment Methods
VisaMastercardAmerican ExpressBitcoin, USDTInteracApple PayGoogle PayPayPal

Discount Coupons

  • Victoria Day - May 18, 2026 8% VICTORIA8
  • Canada Day - July 1, 2026 10% CANADADAY10
  • Labour Day - September 7, 2026 6% LABOUR6
  • Thanksgiving (Canada) - October 12, 2026 9% THANKS9
  • Boxing Day - December 26, 2026 12% BOXING12

Brand Names

Also known as (by country):
CountryBrand Names
Canada
Apo-Losartan/HCTZ
United Kingdom
Cozaar-Comp
France
Fortzaar Losartan/Hydrochlorothiazide Biogaran
Australia
Cozaar Comp
Germany
Lorzaar Plus
Italy
Hizaar
Belgium
Cozaar Plus Loortan Plus

FAQ

Losartan-hydrochlorothiazide is a prescription medicine when purchased from local pharmacies in Canada. Our store policy allows you to place an order without a prescription and have it sent by mail. A prescription is still important for making sure this treatment is appropriate for you.

Take unused or expired tablets to a pharmacy or an authorized medication take-back program when available. Keep them out of household garbage and away from children and pets until they can be disposed of safely.

A generic losartan-hydrochlorothiazide product contains the same active ingredients: losartan and hydrochlorothiazide. The manufacturer, tablet appearance, packaging, and inactive ingredients may differ from a brand-name product.

Store the tablets at 25°C; excursions between 15°C and 30°C are permitted. Keep the container tightly closed and protected from light.

No. Losartan-hydrochlorothiazide is contraindicated during pregnancy because medicines acting on the renin-angiotensin system can seriously harm or cause death to the developing fetus. It should also be avoided while breastfeeding because hydrochlorothiazide passes into breast milk and may reduce milk production, while information on losartan in human milk is lacking.

Losartan-hydrochlorothiazide is used to treat high blood pressure in adults. It combines an angiotensin II receptor blocker with a thiazide diuretic and may be used when combination treatment is appropriate.

Description

Introduction

The medication Hyzaar is used to treat hypertension. This medication is a mixture of two drugs: a thiazide "water pill"/diuretic and an angiotensin receptor blocker. Blood vessels enlarge and relax when using Hyzaar. By increasing the volume of urine produced, the thiazide diuretic reduces the amount of extra water and salt in your body. Maintaining blood pressure control can help prevent kidney issues, heart attacks, and strokes.

Your doctor may prescribe this medication for other reasons. If you would like additional information on this medication, contact your doctor.

Even if your condition seems to be improving, don't stop taking Hyzaar earlier than your doctor has instructed. If you stop taking the drug too soon, it could make things worse. Until you know how this drug affects you, take caution when operating machinery, driving, climbing, or performing other risky actions. Avoid consuming alcohol. Never provide Hyzaar to a child without first consulting a physician.

How Should I Use Hyzaar?

Note: Don't give this medication to anyone else. Please take it as prescribed by your doctor, neither more nor less.

Hyzaar is administered orally with food, milk, or an antacid to avoid stomach upset. Unless your doctor instructs you otherwise, you may also take it with a full glass of water. Avoid lying down for half an hour after taking this medication. Administer the dosages regularly.

Excessive or Missed Dose

Any medication used in excess might have adverse effects on your health. Get in touch with your healthcare provider right away if you suspect an overdose.

If you forget to take a dose, take it as soon as possible. Never take two doses at once if your next dose is almost due. Take one dosage at a time.

Which Medical Issues or Symptoms Should I Notify a Doctor About Before Using Hyzaar?

Consult a physician if any of the following apply to you or have previously affected you:

  • allergies or asthma;
  • lupus;
  • an allergy to sulfa medications;
  • liver or kidney problems;
  • gout;
  • low or high blood potassium levels;
  • congestive cardiac dysfunction;
  • diabetes.

Adverse Effects

If you have any of the following severe side effects, get in touch with your doctor right away:

  • allergy symptoms such as a skin rash, lips, tongue, and facial swelling, hives, itching, and breathing difficulties;
  • reduced or absent urination, as opposed to increasing urination;
  • quick increase in weight;
  • fainting and swelling;
  • pale complexion, dizziness, pounding or rapid heartbeat, and elevated heart rate;
  • confusion;
  • sleepiness, easy bruising or bleeding, dry mouth, increased thirst, jaundice (yellowing of the skin or eyes), convulsions, or a restless feeling.

Less severe adverse effects:

  • skin rash;
  • sore throat;
  • dry cough;
  • backache;
  • nausea and dizziness;
  • stuffy or runny nose.

Other adverse effects could occur; this is not an exhaustive list. Tell your doctors about all the side effects you encounter.

Warning

Try not to get too hot or dehydrated when exercising in hot weather. Speak with your doctor to determine how much liquids you should consume daily. Unless advised otherwise by your doctor, stay away from potassium supplements and salt replacements while undergoing therapy. If taken during the latter six months of pregnancy, this medication has the potential to damage or even kill the fetus. See your doctor right away if you become pregnant or suspect you might be pregnant. Avoid abrupt standing or sitting up, particularly if you are an elderly patient. Regularly check your blood pressure. Tests for your renal function can also be necessary.

This page does not aim to cover all the information about Hyzaar, including safety measures, medication interactions, side effects, usage, recommendations, allergic reactions, or warnings.

How to Store

Hyzaar needs to be kept in a firmly closed container at room temperature. Keep out of the light, heat, and moisture. Store away from sinks and bathrooms. Hyzaar should be kept out of children's reach and away from animals.

Medically reviewed by
John Buducci
Pharmacology expert
Updated August 11, 2026

Customer questions

Asked by Sophie Tremblay, Montreal, Canada

My order arrived in Montreal after several very cold days. What should I check before I use the tablets?

Answered by Support team

Check that the package is intact, dry, and clearly labelled, and that the tablets have no unusual damage or change in appearance. Keep them at 25°C, with permitted excursions from 15°C to 30°C; because the actual transport temperature and duration are unknown, do not use tablets from a compromised package until the issue is checked.

Asked by Daniel Chen, Vancouver, Canada

I found what appears to be the same generic online for about half the price. Why should I order from you instead?

Answered by Support team

We stand behind the quality of the generic medicines we offer. We cannot verify another seller's sourcing, manufacturer, handling, or whether a similarly named lower-priced product is truly equivalent; that is a risk only you can weigh against the savings.

Asked by Priya Patel, Guelph, Canada

I live in Guelph. Can I enter my postal code before ordering to see whether this medicine can be shipped to me?

Answered by Support team

Yes. Enter your Guelph postal code and delivery address at checkout to check whether shipping is available for your location before completing the order.

Asked by Noah McLeod, Yellowknife, Canada

I'm in Yellowknife and deliveries can be limited here. How can I find out whether you can send this medicine to my address?

Answered by Support team

Please enter your Yellowknife address and postal code at checkout to confirm whether the destination can be served. Availability for remote routes can vary, so it should be checked for the specific address before ordering.

Asked by Aisha Singh, Oshawa, Canada

I have type 2 diabetes and take medication for it. Is there anything special to consider before starting losartan-hydrochlorothiazide?

Answered by Support team
Medical reviewed by Wendy Hayes

Yes. The hydrochlorothiazide component can affect blood glucose control, so glucose monitoring and adjustment of diabetes treatment may sometimes be needed. This combination must not be used with aliskiren in people with diabetes; a prescriber or pharmacist should review your current medicines before treatment starts.

Product specifications

Active ingredientLosartan-hydrochlorothiazide
Drug classAngiotensin II receptor blocker (ARB) with thiazide diuretic
Dosage formFilm-coated tablet
Available strengths50 mg/12.5 mg, 100 mg/12.5 mg, 100 mg/25 mg
RouteOral
StorageStore at 25°C; excursions permitted to 15°C to 30°C. Keep the container tightly closed and protect from light.
ATC codeC09DA01

Regulatory information

More information