Cymbalta (Duloxetine)

Cymbalta
4.76 ratingsReviews
Generic:
Duloxetine
Indications:
anxiety depression diabetic peripheral neuropathy fibromyalgia
Analogs:
Malegra Dxt Malegra Dxt Plus
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Cymbalta 20 mg

Quantity Price per tablet You save Total price
30 C$3.31 - C$99.40
60 C$2.36 C$57.40 C$141.40
90 C$1.99 C$119.00 C$179.20
120 C$1.83 C$177.80 C$219.80
180 C$1.66 C$296.80 C$299.60
270 C$1.56 C$473.20 C$421.40
360 C$1.50 C$653.80 C$539.00

Cymbalta 30 mg

Quantity Price per tablet You save Total price
30 C$4.01 - C$120.40
60 C$2.82 C$71.40 C$169.40
90 C$2.44 C$141.40 C$219.80
120 C$2.24 C$212.80 C$268.80
180 C$2.05 C$354.20 C$368.20
270 C$1.91 C$567.00 C$516.60

Cymbalta 40 mg

Quantity Price per tablet You save Total price
30 C$4.20 - C$126.00
60 C$2.99 C$72.80 C$179.20
90 C$2.57 C$147.00 C$231.00
120 C$2.38 C$218.40 C$285.60
180 C$2.19 C$362.60 C$393.40
270 C$2.06 C$576.80 C$557.20

Cymbalta 60 mg

Quantity Price per tablet You save Total price
30 C$3.92 - C$117.60
60 C$3.06 C$51.80 C$183.40
90 C$2.78 C$102.20 C$250.60
120 C$2.63 C$155.40 C$315.00
180 C$2.49 C$257.60 C$448.00
270 C$2.40 C$410.20 C$648.20

Manufacturers

Apotex Inc.Eli Lilly and CompanyGenPharma International Pvt. Ltd.Sun Pharmaceutical Industries Ltd.

Payment & Shipping

Package Example

Your order is securely packed and usually ships within 24 hours. Here is what a typical parcel looks like.

It is about the size of a regular letter (24x11x0.7 cm) and does not show any details of what is inside.

Front View
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Back View
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Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over C$420.00Estimated delivery to Canada: 4-7 days
Standard Free for orders over C$280.00Estimated delivery to Canada: 14-21 days
EMSCanada Post
Payment Methods
VisaMastercardAmerican ExpressBitcoin, USDTInteracApple PayGoogle PayPayPal

Discount Coupons

  • Victoria Day - May 18, 2026 8% VICTORIA8
  • Canada Day - July 1, 2026 10% CANADADAY10
  • Labour Day - September 7, 2026 6% LABOUR6
  • Thanksgiving (Canada) - October 12, 2026 9% THANKS9
  • Boxing Day - December 26, 2026 12% BOXING12

Brand Names

Also known as (by country):
CountryBrand Names
Canada
Apo-Duloxetine
United Kingdom
Yentreve
Italy
Xeristar
Belgium
Yentreve

FAQ

Duloxetine is a prescription-only medicine when purchased from local pharmacies in Canada. Our store policy allows you to place an order without a prescription and have it sent by mail. A prescriber should still determine whether duloxetine is appropriate for you.

Contact the prescriber managing your treatment promptly. Duloxetine during pregnancy requires an individual benefit-risk assessment, particularly because use late in pregnancy can cause newborn adaptation or withdrawal symptoms. Do not stop it suddenly unless a clinician tells you to, as abrupt discontinuation can cause withdrawal symptoms.

A generic duloxetine product contains duloxetine, the same active ingredient as Cymbalta. The manufacturer, capsule appearance, and inactive ingredients can differ between products, so check the received package label for its specific details.

Duloxetine is an SNRI used for major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, and fibromyalgia. It may also be used for certain chronic musculoskeletal pain conditions. The appropriate use depends on the diagnosis and treatment plan.

During pregnancy, duloxetine should be used only after a prescriber weighs the potential benefit against fetal and newborn risks. Breastfeeding while taking duloxetine is not recommended because the medicine passes into breast milk and infant safety has not been established.

Description

A well-known medication known as an antidepressant, noradrenaline, and serotonin reuptake inhibitor (SNRI) is called Cymbalta. It lessens diabetics' symptoms of peripheral neuropathy, fibromyalgia, melancholy, and generalized anxiety disorder (GAD).

Ask your doctor if you require more specific information regarding this medication's effects and mode of action.

Warning: Cymbalta makes you more photosensitive. Severe burning could result from this. If it's inevitable that you will be in the sun, then you should wear protective clothes and use sunscreen. Avoid consuming alcohol. There could be harmful adverse effects from this that could endanger your health. Dizziness or coordination trouble are possible side effects when using this medication. 

Don't drive before you know how this solution affects you. Even if you feel better after starting medication earlier than your doctor has suggested, abruptly stopping the medication might make some conditions worse. Consult a physician before administering Cymbalta to kids.

Cymbalta_30mg

If you currently have any of the following conditions, let your doctor know: glaucoma, allergies, suicidal thoughts, drug usage history in the past, blood clotting disorder or bleeding; nursing, pregnancy, or you intend to get pregnant; kidney or liver disease; heart attack; cardiac issues, stroke, epilepsy, or seizures, bipolar disorder (manic-depressive).

This medication is sold in capsule form. One or two pills are typically prescribed per day. You should use this medication on a regular basis. After taking the capsule, drink some water. Additionally, throughout the course of treatment, drink several glasses of water to protect your kidneys. It can be taken with or without food. You can take the medication with meals to reduce the possibility of stomach discomfort and to aid in the body's absorption of the medication. You have to take the pills whole. The capsule should not be chewed on, cracked, or crushed.
If you forget to take the dose, take it as soon as possible. If your next dose is almost due, do not take two doses. After taking just one dose, stick to your regular routine.

Large dosages can have detrimental effects on your health. Notify your doctor right away if you have taken too much of the medication.

Avoid taking the medication with any of the following: venlafaxine, St. John's Wort, Nefazodone, some phentermine, and other diet medicines such as fenfluramine, dexfenfluramine, and sibutramine, Procarbazine, Tryptophan, SSRIs such as fluoxetine, citalopram, fluvoxamine, sertraline, escitalopram, paroxetine, and Thioridazine, and MAOIs such as Eldepryl, Parnate, Carbex, Nardil, and Marplan.

Additionally, the following may interact with this remedy: cimetidine-containing medications for heart rhythm problems or blood pressure, some antibiotics (enoxacin, ciprofloxacin), and additional medications for psychosis, mental depression, anxiety, and manic episodes.

This list of exchanges may be incomplete. For further specific information, speak with your doctor. Also, talk to your doctor about using your medication in conjunction with food, drink, or tobacco.

Cymbalta_60mg

Be aware of the following side effects: chest pain, breathing difficulties; appetite loss; liver issues; skin, and eye yellowing; nausea and vomiting; spasms, tremor, numbness, or tingling in your hands or feet caused by your muscles; allergies (swelling of the tongue, face, throat, or lips; itching, hives, trouble breathing; skin rash or swelling); headache, ringing in the ears, dizziness, and hearing loss; mental and mood disorders (such as disassociation from reality, disorientation, agitation, clouded vision, and hallucinations); palpitations, a rapid, hammering, or irregular pulse; fever with increased perspiration, thoughts of suicide, or other mood swings; diarrhea, loss of bladder control, and trouble peeing (urinary retention).

Get in touch with your doctor right away if any of these adverse effects worsen or continue. There may be other negative effects that are not included in this list. See your physician if you encounter any other adverse effects.

Cymbalta should be stored at room temperature, 15 to 30 degrees Celsius (59 to 86 degrees Fahrenheit), with the container well closed and out of direct sunlight, heat, and moisture. Keep medication out of the reach of kids and pets.

Medically reviewed by
John Buducci
Pharmacology expert
Updated August 11, 2026

Customer questions

Asked by Alyssa Martin, Whitehorse, Canada

I live outside Whitehorse, and deliveries can be limited where I am. How can I find out whether you can ship duloxetine to my address?

Answered by Support team

Enter your full Whitehorse-area delivery address during checkout to check whether the destination can be served. Shipping availability can vary for remote routes, so it cannot be confirmed for every address in advance.

Asked by Daniel Chen, Windsor, Canada

My duloxetine package arrived in Windsor after sitting outside during a very cold spell. What should I check before I take the capsules?

Answered by Support team

Check that the Windsor package is intact, dry, and free of damaged or opened capsules, then compare the label with the product you ordered. Duloxetine should be stored at 25°C, with permitted excursions from 15°C to 30°C; because the actual exposure is unknown, do not use capsules that appear compromised until the discrepancy is checked.

Asked by Priya Sandhu, Kelowna, Canada

Before I order from Kelowna, can I use my postal code to see whether this medicine can be shipped to me?

Answered by Support team

Yes, enter your Kelowna postal code and delivery address during checkout to check destination eligibility. Availability is address-specific, so entering the full address provides the relevant result.

Asked by Megan O'Connor, Edmonton, Canada

I previously took branded Cymbalta and have sensitivities to some capsule ingredients. Will the inactive ingredients be the same in the product I receive?

Answered by Support team

They may not be the same. Generic products can use different inactive ingredients, and the exact supplied formulation is not known in advance; review the ingredient list on the received package before use if you have a known sensitivity.

Asked by Noah Tremblay, St. Catharines, Canada

I take trazodone some nights for sleep and have just been prescribed duloxetine. Can I take them together?

Answered by Support team
Medical reviewed by John Buducci

Trazodone and duloxetine can both increase serotonin activity, which can raise the risk of serotonin syndrome and additive drowsiness or dizziness. Do not start or combine them without the prescriber or pharmacist reviewing the doses and your other medicines; seek urgent help for agitation, fever, sweating, tremor, diarrhoea, or confusion.

Product specifications

Active ingredientDuloxetine
Drug classSerotonin-norepinephrine reuptake inhibitor (SNRI)
Dosage formDelayed-release capsules
Available strengths20 mg, 30 mg, 40 mg, 60 mg
RouteOral
StorageStore at 25°C; excursions permitted between 15°C and 30°C. Keep the container tightly closed and protect from moisture.
ATC codeN06AX21

Regulatory information

Canada: medicine status
Registration statusDuloxetine delayed-release capsules, including Cymbalta-branded and generic products, are authorized prescription drug products in Canada; the DIN, marketed status, and authorized strengths depend on the specific manufacturer and product.
Prescription statusDuloxetine is a prescription-only medicine in Canada.
Official product informationHealth Canada's Drug Product Database provides the current product listing and, where available, the product monograph and consumer information for a specific DIN.
Public drug-plan coveragePublic reimbursement is not universal; coverage for duloxetine varies by provincial or territorial formulary, plan eligibility, and any clinical coverage criteria.
Safety monitoringSuspected adverse reactions to duloxetine can be reported to Health Canada through the Canada Vigilance Program.

More information