Azulfidine (Sulfasalazine)

Azulfidine
4.54 ratingsReviews
Generic:
Sulfasalazine
Indications:
ulcerative colitis
Analogs:
Salazopyrin Mesalamine Balsalazide Olsalazine Methotrexate Hydroxychloroquine Leflunomide Asacol Pentasa Lialda Plaquenil Arava Colazal Dipentum
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Azulfidine 500 mg

Quantity Price per tablet You save Total price
60 C$2.89 - C$173.60
90 C$2.60 C$26.60 C$233.80
120 C$2.45 C$53.20 C$294.00
180 C$2.25 C$116.20 C$404.60
270 C$2.15 C$200.20 C$581.00

Manufacturers

AlphapharmIpca Laboratories Ltd.Pfizer

Payment & Shipping

Package Example

Your order is securely packed and usually ships within 24 hours. Here is what a typical parcel looks like.

It is about the size of a regular letter (24x11x0.7 cm) and does not show any details of what is inside.

Front View
Front View
Side View
Side View
Back View
Back View
Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over C$420.00Estimated delivery to Canada: 4-7 days
Standard Free for orders over C$280.00Estimated delivery to Canada: 14-21 days
EMSCanada Post
Payment Methods
VisaMastercardAmerican ExpressBitcoin, USDTInteracApple PayGoogle PayPayPal

Discount Coupons

  • Victoria Day - May 18, 2026 8% VICTORIA8
  • Canada Day - July 1, 2026 10% CANADADAY10
  • Labour Day - September 7, 2026 6% LABOUR6
  • Thanksgiving (Canada) - October 12, 2026 9% THANKS9
  • Boxing Day - December 26, 2026 12% BOXING12

Brand Names

Also known as (by country):
CountryBrand Names
Canada
Salazopyrin
United Kingdom
Salazopyrin Salazopyrin EN-Tabs
France
Salazopyrine
Australia
Pyralin EN Salazopyrin
New Zealand
Salazopyrin
Germany
Azulfidine RA
Italy
Salazopyrin EN
Belgium
Salazopyrine

FAQ

A prescription is required to obtain sulfasalazine from local pharmacies in Canada. Our store policy allows you to place an order without a prescription and have the medicine sent by mail.

Yes. Tell the surgeon, dentist, anaesthesia team, or clinician that you take sulfasalazine, along with all other medicines and supplements. Do not stop it on your own; whether treatment should be continued or adjusted depends on the procedure and the condition being treated.

The 500 mg tablets listed contain sulfasalazine, which is the active ingredient associated with Azulfidine. Products with the same active ingredient can still differ in manufacturer, appearance, packaging, and inactive ingredients.

Take the 500 mg tablets by mouth exactly as prescribed, preferably with food and a full glass of water to help limit stomach upset. Doses are commonly spaced as evenly as practical through the day, and adequate fluid intake is important because dehydration can increase the risk of crystals or stones in the urine. The prescribed dose depends on the condition being treated and individual factors.

Description

General Information

Azulfidine is a medication that has anti-inflammatory and anti-microbial qualities. It is a mixture of 5-aminosalicylic acid and sulfapiridin. The medication is absorbed in small amounts from the colon's lumen and then evenly distributed within the connective tissue. Because Azulfidine is more readily absorbed (up to 30% of the dose), it primarily has a broad anti-inflammatory effect.

According to the National Library of Medicine, Azulfidine is prescribed for the following conditions:

  1. Rheumatoid arthritis.
  2. Polyarticular Juvenile Idiopathic Arthritis.
  3. Ulcerative colitis.

There are also non-FDA approved (off-label) indications:

  • Ankylosing Spondylitis;
  • Crohn's Disease;
  • Psoriatic Arthritis.

See your physician before using the medication.

How to Take

Azulfidine is given with 240-250 ml of drinking water, preferably before meals.

azulfidina-sulfasalazina-500mg-60grageas

Side Effects and Contraindications

Side effects frequently occur when the medication builds up a high concentration in the blood plasma. Patients with delayed occurrence of sulfapiridin acetylation rate may experience such a condition. Itchy skin, fever, headaches, gastrointestinal tract issues, and erythema are common adverse effects of the medication.

Restrictions

  • hypersensitivity to the medication's ingredients;
  • severe liver and kidney conditions;
  • up to two years of age.

Period of Pregnancy and Nursing

Pregnancy-related use of Azulfidine is permitted, but only in extreme cases. Expectant mothers are advised to select the lowest effective dosage. Breastfeeding is discontinued if medication is required because it is well excreted in breast milk.

Interactions

Digoxin and folic acid are less absorbed when taking Azulfidine, which strengthens the anticoagulant agents.

Please keep Azulfidine at a temperature of no more than 25°C in a dark place.

 

Medically reviewed by
John Buducci
Pharmacology expert
Updated August 11, 2026

Customer questions

Asked by Megan Clarke, Regina, Canada

I live in Regina. Can I enter my postal code before ordering to see whether these tablets can be shipped to me?

Answered by Support team

Yes. Enter your Regina postal code and delivery address at checkout to check the options available for your order. Availability can vary by destination, so it should be confirmed before payment.

Asked by Daniel Martin, Guelph, Canada

My package arrived in Guelph after sitting outside in very cold weather. What should I check before I take the tablets?

Answered by Support team

Check that the container is intact, dry, and tightly closed, and that the tablets are not cracked, discoloured, wet, or otherwise damaged. Store them at 20°C to 25°C; because the actual temperature and duration of cold exposure are unknown, do not use tablets from a compromised package until the issue is checked.

Asked by Ava Karetak, Iqaluit, Canada

I'm in Iqaluit and deliveries can be limited here. How can I find out whether you can send this medicine to my address?

Answered by Support team

Please enter your complete Iqaluit address and postal code at checkout to check whether shipping is available for your destination. We cannot confirm availability for every remote route in advance.

Asked by Noah Bennett, Calgary, Canada

I have used a brand-name sulfasalazine product before. What does "bioequivalent" mean when I'm comparing it with a generic?

Answered by Support team

For a generic medicine, bioequivalent means it has been shown to deliver the active ingredient into the body at a comparable rate and extent to its reference product under the required testing standards. That term does not mean every supplied product has the same manufacturer, appearance, or inactive ingredients.

Asked by Priya Shah, Winnipeg, Canada

I have diabetes and my clinic checks my blood glucose during routine bloodwork. Can sulfasalazine affect the test result?

Answered by Support team
Medical reviewed by Wendy Hayes

Sulfasalazine or its metabolites can interfere with certain NAD(H)-dependent laboratory glucose assays and may produce a misleading result. Tell the clinic or laboratory that you take sulfasalazine so an unexpected reading can be confirmed with an appropriate method.

Product specifications

Active ingredientSulfasalazine
Drug classAminosalicylate anti-inflammatory
Dosage formTablet
Available strengths500 mg
RouteOral
StorageStore at 20°C to 25°C; excursions permitted from 15°C to 30°C. Keep the container tightly closed and away from moisture.
ATC codeA07EC01

Regulatory information

More information