Paxil CR is a well-known selective serotonin reuptake inhibitor (SSRI) antidepressant medication. It reduces symptoms of major depression, fibromyalgia, PTSD, anxiety disorders, premenstrual dysphoric disorder (PMDD), and obsessive-compulsive disorder (OCD).
Tell your doctor if you are using any of the following medications, which are referred to as monoamine oxidase inhibitors (MAOI): phenelzine (Nardil), isocarboxazid (Marplan), tranylcypromine (Parnate), linezolid (Zyvox), or selegiline (Emsam, Zelapar, Eldepryl).
Which Medical Issues or Symptoms Should I Notify a Doctor About?
Consult a physician if any of the following apply to you or have previously affected you:
- Seizures, heart attacks, cardiac problems, strokes, and epilepsy during electroconvulsive therapy;
- Glaucoma;
- Suicidal ideas or actions;
- Manic-depressive bipolar disorder;
- Liver or kidney illness;
- Pregnancy, nursing, or intending to become pregnant;
- An unusual or adverse reaction to paroxetine, other medications, foods, preservatives, or dyes;
- Stomach or intestinal bleeding.
Forms of Paxil Cr and Dosage
Paxil Cr is available in liquid or tablet form for oral consumption.
| Dosage Strength |
Formulation |
Typical Dosage Range |
| 12.5 mg |
Extended-Release Tablets |
12.5 mg to 62.5 mg per day |
| 25 mg |
Extended-Release Tablets |
12.5 mg to 62.5 mg per day |
| 37.5 mg |
Extended-Release Tablets |
12.5 mg to 62.5 mg per day |
It is often taken in the morning or evening once a day. Take this medication with some beverages. When using Paxil CR, drinking multiple glasses of water daily is critical to saving your kidneys. It is acceptable to take it with or without food. Taking the medication with meals is preferable to help your body absorb it and ease stomach discomfort.
You should swallow the whole pill. Never eat, break, or crush it. To distribute the medicine equally, shake the suspension thoroughly before using it. Use a measuring spoon or medicine cup with a designated marking to ensure you take the right amount of medicine.
Paxil CR dosage varies according to patients and the conditions being treated. It goes without saying that you should speak with your doctor before using this drug and follow your doctor's directions.
Interactions May Occur with the Following Medications:
Digoxin, linezolid, procyclidine, phenobarbital, aspirin, and aspirin-like medications, fosamprenavir, theophylline, cimetidine, and migraine headache medications such as eletriptan, almotriptan, naratriptan, frovatriptan, rizatriptan, zolmitriptan, sumatriptan, NSAIDs, phenytoin, ibuprofen, naproxen, ritonavir, medications for anxiety, depression, or psychotic disorders, and blood clot-preventing/treating medications such as enoxaparin, warfarin, and dalteparin.
This list of interactions may be incomplete. Give your doctor a complete list of all medications, herbal remedies, nutritional supplements, and over-the-counter medications you take. Additionally, let them know whether you smoke, take illegal substances, or drink alcohol. Certain things might interfere with your medication.
Adverse Effects of This Medication
- An allergic reaction could cause breathing difficulties, hives, itching, lip, face, tongue, or throat swelling, as well as skin rashes or swelling;
- difficult or prolonged erection in men;
- change in weight and appetite;
- palpitations: a rapid, hammering, or irregular heartbeat;
- mental and emotional shifts, including disorientation, restlessness, confusion, hallucinations, and blurred vision;
- breathing issues and chest pain;
- fever and increased perspiration;
- muscle stiffness, spasms, tingling in your hands or feet (tremor), or numbness;
- bloating, gas in the stomach, cramping, indigestion, or disturbed stomach;
- vomiting and nausea;
- unusual bruises or bleeding;
- headache, lightheadedness, ear ringing, or hearing loss;
- urinary retention, diarrhea, red or black feces, blood in the urine, and vomiting;
- having trouble falling asleep;
- issues with the liver, eyes, and skin.
Notify your doctor right away if problems continue or get worse. Other negative effects could occur; this is not an exhaustive list. See your physician or pharmacist if you have any other side effects not on this list.
Paxil CR should be kept in a firmly closed container at room temperature, between 15 and 30 degrees Celsius (59 and 86 degrees Fahrenheit). Keep out of the light, heat, and moisture. Store away from sinks and bathrooms. Paxil CR should be kept out of children's reach and away from animals.
