Advair Diskus (Fluticasone and Salmeterol)

Advair Diskus
4.73 ratingsReviews
Generic:
Fluticasone and Salmeterol
Analogs:
Seretide Wixela Inhub Airduo Respiclick Symbicort Dulera Breo Ellipta Fostair Trelegy Ellipta
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Advair Diskus 100mcg+50mcg

Quantity Price per inhaler You save Total price
2 £21.85 - £43.71
3 £15.80 £18.15 £47.41

Advair Diskus 250mcg+50mcg

Quantity Price per inhaler You save Total price
1 £80.01 - £80.01
2 £66.30 £27.41 £132.60
3 £60.99 £57.04 £182.98
4 £58.71 £85.19 £234.83
5 £57.49 £112.60 £287.43

Advair Diskus 500mcg+50mcg

Quantity Price per inhaler You save Total price
1 £86.67 - £86.67
2 £72.23 £28.89 £144.46
3 £67.66 £57.04 £202.98
4 £65.19 £85.93 £260.76
5 £63.71 £114.82 £318.54

Manufacturers

GlaxoSmithKlineGlaxoSmithKline plcMylan PharmaceuticalsSandoz

Payment & Delivery

Package Example

Your order is securely packed and usually dispatched within 24 hours. Here is what a typical parcel looks like.

It is about the size of a regular letter (24x11x0.7 cm) and does not show any details of what is inside.

Front View
Front View
Side View
Side View
Back View
Back View
Delivery Times
Delivery MethodEstimated delivery
Express Free for orders over £222.24Estimated delivery to the UK: 4-7 days
Standard Free for orders over £148.16Estimated delivery to the UK: 14-21 days
EMSRoyal Mail
Payment Methods
VisaMastercardAmerican ExpressJCBBitcoin, USDTApple PayGoogle PayPayPalKlarnaClearpay

Discount Coupons

  • New Year's Day - 1 January 2026 9% NEWYEAR9
  • Valentine's Day - 14 February 2026 6% VALENTINE6
  • St David's Day - 1 March 2026 4% DAVID4
  • St Patrick's Day - 17 March 2026 5% PATRICK5
  • St George's Day - 23 April 2026 4% GEORGE4
  • May Day - 1 May 2026 5% MAYDAY5
  • Halloween - 31 October 2026 6% HALLOWEEN6
  • Guy Fawkes Night - 5 November 2026 5% GUY5
  • Christmas Eve - 24 December 2026 9% XMASEVE9
  • Christmas Day - 25 December 2026 10% XMAS10
  • Boxing Day - 26 December 2026 10% BOXING10
  • New Year's Eve - 31 December 2026 8% NYE8

Brand Names

Also known as (by country):
CountryBrand Names
United Kingdom
AirFluSal Forspiro Seretide Accuhaler
Australia
Seretide Accuhaler
New Zealand
Seretide
United States
Wixela Inhub

FAQ

In the United Kingdom, fluticasone and salmeterol inhalers are prescription-only medicines when bought from local pharmacies. Our store policy allows you to place an order without a prescription and have the product sent by mail. It is still important to use this maintenance inhaler only on appropriate medical advice.

Do not use an inhaler that is cracked, wet, visibly damaged or otherwise altered until it has been checked. Keep it in its protective foil pouch until first use and compare the active ingredients, strength, dosage form, package label, batch number and expiry date with the order details. A change in appearance does not by itself identify the cause, but a compromised device or package should not be used.

Not necessarily. Inactive ingredients can differ between manufacturers and presentations, and the exact formulation supplied for an order should be confirmed from its package leaflet or label. This is particularly important if you have an allergy or sensitivity to an excipient, including a severe milk-protein allergy.

During pregnancy, use should be considered only when the expected benefit of keeping asthma or COPD controlled outweighs any possible risk to the fetus. Do not make a universal decision to stop or continue treatment without discussing it with the clinician managing your respiratory condition. During breastfeeding, a risk to the infant cannot be excluded, so the benefits of breastfeeding and the mother's need for treatment should be weighed individually.

Fluticasone and salmeterol inhalation powder is a regular maintenance treatment for asthma. The 500 mcg/50 mcg strength may also be used for symptomatic treatment of chronic obstructive pulmonary disease in adults. It is not intended to relieve a sudden attack of breathlessness.

Description

Introduction

Advair diskus (Salmeterol/Fluticasone) is a combination of a bronchodilator and a corticoid; it is prescribed to treat and prevent or lessen the symptoms of chronic lung disorders (e.g., emphysema, bronchitis, COPD) and asthma (e.g., crackling, painful respiration). Asthma is well treated with Advair Diskus. It reduces inflammation and widens the lungs' airways, which lowers bronchiolar bulging and weakens the muscles.

Note: Using Advair Diskus to immediately stop an asthma attack won't work. Other quick-relief medications or inhalers must be taken in the event of an asthma attack or abrupt dyspnea.

Before Treatment

Consult a physician if any of the following apply to you or have previously affected you: 

  1. Consuming any additional medications, herbal remedies, or dietary supplements using an inhibitor of monoamine oxidase flare-up of COPD.
  2. Allergy to foods, medications, or other things.
  3. Bacterial, fungal, parasitic, or viral infection.
  4. Osteoporosis or you are at risk of developing it.
  5. If you are attempting to conceive, breastfeeding, or are pregnant.

Advair-Diskus

How Is Advair Diskus Taken?

Patient Age Dosage Frequency
Under 4 1 inhalation Twice daily (morning and evening)
4 and above 100/50 mcg Twice daily (morning and evening)

Ask your doctor if there is another dosage that you should take. Always heed the advice of your physician and/or the directions found on the label of any prescription medication.

Take the dose as soon as you remember if you miss it. Take just one dose if it's time for your next one. The dosage doesn't need to be doubled.

Overdosing on any medication can harm your health. See your doctor as soon as possible if you think you may have overdosed.

Possible Interactions

Advair Diskus May Interact With the Following:

  1. Chloroquine.
  2. Probucol.
  3. Methadrine.
  4. Halofantrine.
  5. Thyroid hormones MAO inhibitors, such as isocarboxazid (Marplan®), phenelzine (Nardil®), tranylcypromine (Parnate®), selegiline (Carbex®, Eldepryl®), and arsenic trioxide.
  6. The cisapride.
  7. Medications (haloperidol, amoxapine, pimozide, maprotiline, risperidone, phenothiazines, tricyclic antidepressants, sertindole, ziprasidone) used to treat depression or mental illness.
  8. Astemizole Droperidol Caffeine.
  9. Medications for colds and breathing problems.
  10. Hormones made of steroids, such as hydrocortisone, dexamethasone, and cortisone.
  11. Bepridil.
  12. Terfenadine.
  13. Beta-blockers, which are frequently prescribed for hypertension or heart issues.
  14. Diuretics or water pills.
  15. Theophylline.
  16. Pentamidine.
  17. Medicines like levofloxacin, gatifloxacin, erythromycin, clarithromycin, gemifloxacin, grepafloxacin, moxifloxacin, linezolid, and sparfloxacin.
  18. Medications such as disopyramide, amiodarone, flecainide, dofetilide, quinidine, procainamide, and sotalol that regulate cardiac rhythm.
  19. Levomethadyl-containing medications for heart disease or excessive blood pressure.
  20. Certain medications (ephedrine, dextroamphetamine, herbal products, and certain ephedra) that aid in weight loss.

This list of interactions may be incomplete. Give your doctor a complete list of all the medications, herbal remedies, nutritional supplements, and over-the-counter medications you take. Additionally, let them know whether you smoke, take illegal substances, or drink alcohol. Certain things might interfere with your medication.

Adverse Effects

Notify your healthcare practitioner if you experience any of the following symptoms: headache, nausea, vomiting, throat irritation, dizziness, diarrhea, tremor, bone or muscular pain, or anxiety.

Immediately stop using Advair Diskus and get emergency medical attention if you have any of the following adverse reactions: breathing difficulties; facial, tongue, or mouth swelling; tightness in the throat; severe or ongoing headaches; seizures; rapid heartbeat, chest pain, tingling or numbness in the hands or feet, acute muscular weakness, spasms, cramps, or changes in vision, sores or white spots on the tongue or mouth, hives; gain in weight, a worsening of asthma symptoms, severe or ongoing bone pain, infection symptoms, unusually high or low energy, or vaginal discharge or odor.

Possible adverse effects are not limited to those listed here. If you have any unusual or concerning side effects, speak with your doctor.

Storage

Advair Diskus should be kept in a firmly closed container at room temperature between 15 and 30 degrees Celsius (59 and 86 degrees Fahrenheit). It should be kept out of light, heat, and moisture, away from sinks and bathrooms, away from animals, and out of children's reach.

You should speak with your doctor before using this medication. This page does not aim to cover all safety measures, medication interactions, side effects, usage, recommendations, allergic reactions, or alerts.

This medication may be prescribed by your doctor for different reasons. If you would like additional information on this medication, contact your doctor.

FAQ

What is Advair Diskus' mechanism of action?

Salmeterol relaxes the muscles surrounding the airways, facilitating easier breathing, while fluticasone lessens inflammation in the airways. When combined, they lessen the chance of asthma attacks and enhance lung function in COPD patients.

To whom is Advair Diskus usually prescribed?

Advair Diskus is prescribed for use in people with COPD and asthma as well as in children four years of age and older.

Is it possible to use Advair Diskus as a rescue inhaler for asthma attacks?

Advair Diskus is not a life-saving inhaler. It is a maintenance drug designed to be taken on a daily basis to control symptoms and stop asthma episodes. As instructed by your healthcare practitioner, use a rescue inhaler if you experience abrupt breathing difficulties.

Medically reviewed by
John Buducci
Pharmacology expert
Updated 11 August 2026

Customer questions

Asked by Aoife Campbell, Lisburn, United Kingdom

I live in Lisburn, Northern Ireland. Can I check whether this inhaler can be delivered to my address before I pay?

Answered by Support team

Yes, enter your Lisburn delivery address when reviewing the destination options at checkout before completing payment. Delivery availability can vary by address, so it cannot be confirmed for every Northern Ireland postcode in advance.

Asked by Daniel Turner, Derby, United Kingdom

I'm in Derby and want to make sure delivery is available to my postcode before ordering. Where can I check?

Answered by Support team

Enter your Derby postcode and delivery address at checkout before payment to see the available destination options. Availability is assessed for the address entered, rather than assumed for all UK postcodes.

Asked by Helen Murray, Newcastle upon Tyne, United Kingdom

I'm ordering from Newcastle upon Tyne. Can this dry-powder inhaler normally travel safely through the post?

Answered by Support team

An inhalation-powder inhaler can normally be sent by mail when it is properly packed and kept in its moisture-protective foil pouch. Once it arrives, check that the pouch and inhaler are dry and undamaged, then store it at 20°C to 25°C away from direct heat and sunlight.

Asked by James Patel, Bristol, United Kingdom

I keep a blue reliever inhaler for sudden wheezing. Can I use this fluticasone and salmeterol inhaler instead when I become short of breath?

Answered by Support team
Medical reviewed by John Buducci

No. Fluticasone and salmeterol inhalation powder is a regular maintenance inhaler and does not work quickly enough for sudden breathing symptoms. Use your prescribed reliever inhaler for an acute episode and seek urgent medical help if symptoms are severe or do not improve.

Product specifications

Active ingredientFluticasone and salmeterol
Drug classInhaled corticosteroid and long-acting beta2-agonist (LABA) combination
Dosage formInhalation powder
Available strengths100 mcg/50 mcg, 250 mcg/50 mcg, 500 mcg/50 mcg
RouteOral inhalation
StorageStore at room temperature between 20°C and 25°C in a dry place away from direct heat or sunlight. Keep the inhaler inside the unopened moisture-protective foil pouch and remove it only immediately before first use. Discard the inhaler 1 month after removing it from the pouch or when the dose counter reads "0", whichever comes first.
ATC codeR03AK06

Regulatory information

United Kingdom: medicine status
Registration statusThe supplied name Advair Diskus is not sufficient to confirm a current UK marketing authorisation for this exact product; UK-authorised fluticasone/salmeterol dry-powder inhalers may be supplied under different brand names and licences.
Prescription statusFluticasone/salmeterol combination inhalers are prescription-only medicines in the United Kingdom.
Patient medicine informationNHS medicine information is available for salmeterol and fluticasone inhalers, including how to use them and important safety advice.Safety monitoringSuspected side effects should be reported through the MHRA Yellow Card Scheme.

More information