Tizanidine 2 mg Tablets

Tizanidine
Generic:
Tizanidine
Indications:
sclerosis spasms
Analogs:
Baclofen Diazepam Dantrolene Cyclobenzaprine Methocarbamol Metaxalone Chlorzoxazone Orphenadrine Zanaflex Sirdalud Carisoprodol
Tizanidine 2 mg tablets are an oral, short-acting alpha-2 agonist muscle relaxant used to manage spasticity. We offer this 2 mg strength in packs of 30, 60, or 90 tablets.
In stock: 19 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Tizanidine 2 mg

Quantity Price per tablet You save Total price
30 $2.37 - $71.00
60 $2.05 $19.00 $123.00
90 $1.93 $39.00 $174.00

Manufacturers

Acorda Therapeutics, Inc.Apotex Inc.Novartis Farmacéutica, S.A.Novartis Farma S.p.A.Novartis Pharma GmbHTeva Canada Limited

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Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over $300.00Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00Estimated delivery to the U.S.: 14-21 days
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Discount Coupons

  • Independence Day - July 4, 2026 10% JULY410
  • Labor Day - September 7, 2026 7% LABOR07
  • Thanksgiving - November 26, 2026 9% THANKS09

Brand Names

Also known as (by country):
CountryBrand Names
United States
Zanaflex
Canada
Apo-Tizanidine Teva-Tizanidine

FAQ

The manufacturer for a future order cannot be guaranteed. Availability may change, so check the received package label for the manufacturer, active ingredient, strength, dosage form, lot number, and expiration date.

These tablets are taken by mouth, with or without food. Take them consistently in relation to meals because food can change tizanidine absorption. The prescribed dose and timing should be followed; a common adult starting dose is 2 mg every 6 to 8 hours as needed, with gradual adjustment when clinically appropriate.

During pregnancy, tizanidine should be considered only after a clinician weighs the potential benefit against potential fetal risk; adequate human pregnancy data are lacking, and animal studies found developmental toxicity. During breastfeeding, human milk data are unavailable, but the medicine may pass into milk, so a clinician should weigh the need for treatment against possible risks to the nursing infant.

Description

Tizanidine 2 mg Tablets and the Main Buying Decision

Tizanidine is a short-acting medicine for managing spasticity, and that short duration is central to deciding whether it fits a prescribed routine. We offer an oral 2 mg tablet in packages of 30, 60, or 90 tablets. We do not offer another strength of this product, so the 2 mg strength and the number of tablets required by the prescribed schedule should be confirmed before choosing a package.

Tizanidine does not provide steady, all-day coverage from a single tablet. Its effects develop and recede over several hours, which allows a prescriber to target periods when relief from spasticity is most important. That flexibility may be useful for some routines, but it also means that dose timing, sedation, food consistency, and the total daily tablet count require careful planning.

Product Identity and Clinical Role

Each tablet contains 2 mg of Tizanidine and is taken by mouth. Tizanidine is a centrally acting skeletal muscle relaxant and alpha-2 adrenergic agonist. It is used to manage spasticity, including muscle tightness, stiffness, and spasms associated with neurological disorders such as multiple sclerosis or spinal cord injury. It controls symptoms while active in the body; it does not cure the underlying neurological condition.

This role differs from that of muscle relaxants used mainly for a short episode of musculoskeletal pain after a strain or sprain. Tizanidine is generally incorporated into a broader management plan that may also include rehabilitation, physical therapy, mobility support, or other prescribed measures. The information available for our current listing does not identify a manufacturer or match the product to a specific FDA application, so those details should not be assumed from the active ingredient, strength, and tablet form alone.

Who Might Discuss Tizanidine With a Prescriber?

Tizanidine may be considered for an adult who needs symptomatic management of spasticity and for whom a short-acting option is appropriate. It should not be selected solely because muscle pain or a spasm is present; the cause and pattern of the symptoms matter. Relevant decision factors include:

  • Timing of symptoms: Intermittent or activity-related periods of troublesome spasticity may call for a different schedule than persistent symptoms throughout the day.
  • Sedation risk: Drowsiness, dizziness, and reduced alertness can affect work, driving, mobility, and fall risk.
  • Blood pressure: Tizanidine can cause hypotension, particularly when treatment starts, the dose changes, or it is combined with other blood-pressure-lowering medicines.
  • Liver and kidney function: Liver injury is a recognized risk, and reduced kidney function can affect how the medicine is cleared.
  • Pregnancy and breastfeeding: Human pregnancy data are limited. There is no direct information about Tizanidine in human milk, although its properties make transfer into milk likely. A clinician should assess the individual benefits and risks.
  • Age: Safety and effectiveness have not been established in pediatric patients.

A prescriber should also know about previous reactions to Tizanidine, current medicines, alcohol use, and any history of fainting or very low blood pressure.

How Does Tizanidine Work in Practice?

Tizanidine stimulates alpha-2 receptors in the central nervous system. This reduces excitatory signaling in spinal pathways involved in excessive muscle tone. In practical terms, it decreases overactive nerve input to the muscles rather than acting directly on muscle fibers.

The central action also explains several important adverse effects. A dose that reduces muscle tightness may cause sleepiness, dizziness, weakness, or a drop in blood pressure. These effects can be more pronounced after a dose increase or when Tizanidine is combined with alcohol, opioids, benzodiazepines, sleep medicines, or other substances that depress the central nervous system. A useful response therefore involves more than reduced stiffness: the person must also be able to tolerate the effects on alertness, balance, and blood pressure.

A Consistent Dosing Routine

Tizanidine is usually started at a low dose and adjusted according to response and tolerability. The exact dose, interval, and maximum daily amount must come from the prescriber and the dispensing label. The availability of a 2 mg tablet can support small prescribed dose adjustments, but it does not make self-directed titration appropriate.

Food affects the absorption of Tizanidine. Taking each dose consistently in the same way with respect to food helps reduce avoidable variation in how the medicine behaves. Switching unpredictably between taking it with food and on an empty stomach can alter exposure and side effects.

Tizanidine should not be stopped abruptly after regular use without clinical guidance, particularly after higher doses or prolonged treatment. Rapid withdrawal has been associated with rebound high blood pressure, a fast heart rate, and increased muscle tightness. If treatment needs to end, the prescriber may recommend a gradual reduction based on the current regimen.

The Package Options We Offer

We currently offer Tizanidine 2 mg tablets in packages of 30, 60, and 90 tablets. Every option contains the same strength and oral tablet form; only the tablet count changes.

  • 30 tablets: The smallest quantity we offer.
  • 60 tablets: Twice the tablet count of the 30-tablet package.
  • 90 tablets: The largest quantity we currently offer.

A package cannot reliably be translated into a fixed number of treatment days without the prescribed tablet count. Because schedules can differ, compare the quantity with the directions on the prescription label rather than assuming that a larger package represents a particular treatment duration. If the prescribed dose has not been settled, confirm it before selecting among our package options.

When Might an Effect Be Noticed?

Tizanidine is absorbed relatively quickly, and an effect may be noticed within approximately one to two hours. Its muscle-relaxing action generally tapers after several hours rather than continuing at a constant level throughout the day. The timing and degree of benefit vary with the dose, food intake, other medicines, and individual response.

Improvement may involve less stiffness, fewer spasms, easier movement, or better tolerance of a planned activity. Complete relief should not be expected, and more sedation does not necessarily mean better control of spasticity. If the effect is too brief, inadequate, or accompanied by troublesome adverse effects, the schedule should be reviewed with the prescriber rather than changed independently.

Safety Priorities Before Use

The main safety concerns include low blood pressure, sedation, dizziness, weakness, liver injury, and impaired coordination. Hallucinations have also been reported. These risks make it important to review the prescribed dose, health history, and complete medication list before the first dose and whenever the regimen changes.

Important Checks Before Taking Tizanidine

Tizanidine should not be used by someone with a known hypersensitivity to Tizanidine or the product ingredients. A clinician may check liver function before or during treatment, particularly when the dose is increased or therapy continues. People with impaired kidney function may require additional caution because clearance can be reduced.

Seek urgent medical help for symptoms such as fainting, severe weakness, difficulty breathing, swelling of the face or throat, or signs of a serious allergic reaction. Yellowing of the skin or eyes, dark urine, persistent nausea, or unusual fatigue should be reported promptly because these symptoms can indicate a liver problem.

Interactions and Everyday Precautions

Tizanidine has clinically important interactions related to sedation, blood pressure, and the CYP1A2 enzyme responsible for much of its metabolism. Important examples include:

  • Ciprofloxacin and fluvoxamine: These combinations are contraindicated because they can markedly increase Tizanidine exposure and cause severe hypotension or excessive sedation.
  • Other CYP1A2 inhibitors: Medicines that inhibit this enzyme may increase Tizanidine concentrations. The prescriber or pharmacist should assess the specific combination.
  • Alcohol and other central nervous system depressants: Opioids, benzodiazepines, sleep medicines, and other sedatives can add to drowsiness and impaired coordination.
  • Blood pressure medicines: Additive effects can increase the likelihood of dizziness, fainting, or a significant drop in blood pressure.
  • Oral contraceptives: These may reduce Tizanidine clearance and increase its effects in some people.

Do not drive, operate machinery, or perform another activity requiring full alertness until the individual response is known. Rise carefully from sitting or lying down, especially early in treatment. A pharmacist or prescriber should review prescription medicines, nonprescription products, supplements, and alcohol use rather than relying only on the most familiar medicine names.

How Does Tizanidine Compare With Alternatives?

No muscle relaxant is universally best. The relevant comparison depends on whether the problem is neurological spasticity or acute musculoskeletal spasm, how long symptom control is needed, and which adverse effects present the greatest concern.

  • Baclofen: Baclofen acts primarily at GABA-B receptors and is also used to manage spasticity. It may be considered when a different duration or mechanism is preferred, but it can also cause sedation and requires careful withdrawal planning.
  • Cyclobenzaprine: Cyclobenzaprine is generally used for short-term acute musculoskeletal spasm rather than neurological spasticity. It is therefore not a direct substitute when the treatment goal is ongoing spasticity management.
  • Diazepam: Diazepam can reduce spasticity but adds important concerns about sedation, tolerance, dependence, and withdrawal.
  • Dantrolene: Dantrolene acts directly on skeletal muscle rather than through the same central alpha-2 pathway. Its different mechanism brings a different balance of benefits and risks, including liver toxicity concerns.

Tizanidine may be a practical option when short-acting, adjustable symptom control is desired and its effects on alertness and blood pressure are manageable. An alternative may be more appropriate when steadier coverage, a different mechanism, or a different adverse-effect profile is needed. That choice requires clinical assessment rather than a simple comparison of tablet counts.

US Prescription Status and Our Ordering Policy

Tizanidine is a prescription-only medicine in the United States. FDA-approved Tizanidine products are indicated for managing spasticity, and official labeling describes contraindications, dosing, warnings, monitoring, and interactions. Suspected serious adverse events or product-quality problems can be reported to the FDA MedWatch program.

The US regulatory classification is separate from our ordering policy. Our checkout does not require a prescription document to be uploaded or faxed for this product. That policy does not change Tizanidine's prescription status or remove the need for a qualified prescriber to determine whether it is appropriate and establish the regimen.

Our support team is available 24/7 by email, online chat, or phone, and a pharmacist is available for product-related questions. Support can clarify general medicine and ordering information but does not replace individual diagnosis, prescribing, or monitoring.

Ordering and Support

To place an order, select one of the 30-, 60-, or 90-tablet options we offer and review the 2 mg strength and quantity before completing our checkout. Our prices and payment amounts are presented in U.S. dollars. Check the directions provided by the prescriber against the selected tablet count, particularly if the regimen uses more than one tablet at a time.

If a product or order detail is unclear, contact our support team by email, online chat, or phone. We avoid promising a treatment duration from package size because the number of days supplied depends on the individual directions. Clinical monitoring, dose changes, and follow-up with the prescriber also take place separately from our ordering process.

The Final Decision

The key points are the exact product, its short duration, and the safety demands of its central alpha-2 action. We offer only Tizanidine 2 mg oral tablets, with package quantities of 30, 60, or 90 tablets. The right quantity depends on the prescribed tablet count rather than a standard course length.

Before choosing a package, confirm that the 2 mg tablet matches the intended regimen, consider how sedation and low blood pressure could affect daily activities, and review liver health, kidney function, pregnancy or breastfeeding, and interacting medicines. If short, targeted periods of symptom control suit the treatment plan, Tizanidine may be a reasonable prescribed option. If steadier coverage or a different adverse-effect profile is needed, discuss an alternative such as Baclofen with the prescriber instead of changing the Tizanidine schedule independently.

Medically reviewed by
Mildred Torres
Pharmacist
Updated August 12, 2026

Product specifications

Active ingredientTizanidine
Drug classSkeletal muscle relaxant
Dosage formTablet
Available strengths2 mg
Route of administrationOral
StorageStore at 77°F; excursions permitted between 59°F and 86°F. Keep the tablets in a tightly closed container, away from moisture and light.
ATC codeM03BX02

Regulatory information

United States: Tizanidine medicine status
FDA approval statusTizanidine is an FDA-approved prescription active ingredient for managing spasticity; FDA-approved products include tablets and capsules, but the supplied 2 mg catalog product cannot be matched to a specific FDA application or manufacturer from the available information.
Prescription statusTizanidine is a prescription-only medicine in the United States.
Official prescribing informationFDA labeling and DailyMed drug labels provide the approved prescribing information, including contraindications, dosing, warnings, and drug interactions for U.S. tizanidine products.Safety reportingSuspected serious adverse events and product-quality problems may be reported to the FDA MedWatch program.

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