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Shipping Times
Shipping Method
Estimated delivery
Express Free for orders over $300.00
Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00
Estimated delivery to the U.S.: 14-21 days
Payment Methods
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Brand Names
Also known as (by country):
Country
Brand Names
United States
Rayos
Canada
APO-PREDNISONETeva-Prednisone
Australia
PanafcortSone
FAQ
Prednisone tablets require a prescription when purchased from local U.S. pharmacies. Our store policy allows Deltasone to be ordered without a prescription and sent by mail. A clinician should still determine whether prednisone is appropriate for you.
Take the missed dose when you remember unless it is nearly time for the next dose. If it is nearly time, skip the missed dose and return to the regular schedule; do not take two doses together. If prednisone has been used for more than a short time, follow the prescriber's instructions carefully because treatment may need to be tapered rather than stopped abruptly.
Not necessarily. Tablets with prednisone as the active ingredient can have different inactive ingredients, such as fillers, binders, coatings, or dyes, depending on the manufacturer. The exact inactive ingredients for the supplied product are not confirmed in advance, so check the received package label or leaflet if you need to avoid a specific ingredient.
A different appearance can occur when the manufacturer or tablet presentation changes and does not by itself show that the medicine is wrong. Compare the active ingredient, strength, dosage form, manufacturer, package label, lot number, expiration date, and tablet imprint when present. Do not take the tablets until the discrepancy is checked if the ingredient, strength, form, imprint, seal, or physical condition appears incorrect.
Store the tablets at 68°F to 77°F; excursions between 59°F and 86°F are permitted. Keep the container tightly closed and protect it from moisture. Keep the medicine out of reach of children and do not use tablets that are visibly damaged or have been stored in compromised packaging.
Prednisone tablets are taken by mouth exactly as directed for the condition being treated. Taking a dose with food or milk can reduce stomach irritation, and a morning dose is often used to better match the body's natural corticosteroid rhythm. The dose, schedule, and any taper are individualized; do not change or abruptly stop a prescribed course without clinical guidance.
During pregnancy, prednisone should be used only after a clinician weighs the expected benefit against potential fetal risks. Prednisone and its active metabolite can pass into breast milk, so breastfeeding requires caution, particularly with higher doses or prolonged treatment. The decision depends on the dose, duration, and need for treatment, so do not start or stop it solely because of pregnancy or nursing.
Possible short-term effects include stomach upset, increased appetite, trouble sleeping, mood changes, fluid retention, and increased blood sugar. Higher doses or longer treatment can increase the risk of infections, elevated blood pressure, bone loss, muscle weakness, eye problems, skin changes, and adrenal suppression. Seek urgent care for signs of a serious allergic reaction, severe mood or behavior changes, black or bloody stools, or symptoms of a serious infection.
Description
Deltasone at a Glance for US Customers
Deltasone is a familiar former US brand name for oral prednisone. Although the Deltasone brand has been discontinued in the United States, the name still appears in older medical records and everyday conversations about prednisone. We use Deltasone as the exact identity of this product listing, while the specifications on this page describe the oral prednisone tablets and strengths we offer. The historical brand name alone does not establish the approval or marketing status of a particular current manufacturer.
Deltasone in the US Pharmacy Landscape
In current US practice, prescriptions and pharmacy labels generally use the generic name prednisone. People may nevertheless recognize Deltasone from previous treatment, family medical records, or older educational material. This distinction matters when comparing products: a familiar historical name is not a substitute for checking the active ingredient, strength, manufacturer information, and labeling supplied with the tablets.
Everyday Use and Best Practices
Prednisone may be prescribed as a brief course, an intermittent treatment, or longer-term therapy, depending on the condition. The dose can vary substantially, and some regimens require gradual dose reduction. Tapering is not necessary for every short course, but suddenly stopping prolonged or high-dose treatment can cause corticosteroid withdrawal and potentially serious adrenal problems. Follow the exact schedule provided by the prescriber responsible for your treatment.
Take the tablets with water and follow the directions on the dispensing label.
Use a written schedule or pill organizer if the daily dose changes during a taper.
Do not double a missed dose unless a prescriber or pharmacist specifically advises it.
Do not change the dose because symptoms improve or side effects occur without seeking clinical advice.
Morning, Evening, and Routine Timing
Once-daily prednisone is often taken in the morning because this more closely follows the body's natural cortisol rhythm and may reduce sleep disruption. Divided-dose regimens and treatment for specific conditions may follow a different schedule. People who work night shifts or have an unusual sleep pattern should ask their prescriber how to align the dose with their routine rather than changing the timing independently.
Taking Deltasone With Food
Prednisone tablets are generally taken with food or milk to reduce stomach irritation. For many people in the United States, pairing a morning dose with breakfast makes it easier to remember, whether breakfast is eggs and toast, cereal, oatmeal, or a bagel. The particular meal is less important than following the prescribed schedule. If coffee worsens heartburn or stomach discomfort, taking the tablet with a more substantial meal and discussing persistent symptoms with a clinician may help.
Alcohol can add to stomach irritation and may compound longer-term concerns such as bone loss, so individual advice is appropriate, particularly during high-dose or prolonged treatment. Do not alter treatment solely because of dietary advice found online.
Safety Priorities and Daily Activities
Prednisone can cause dizziness, blurred vision, headache, insomnia, mood changes, or confusion in some people. These effects may be more noticeable at higher doses, including doses in the 20 mg to 40 mg range. Avoid driving or operating machinery until you know how the medicine affects you.
Systemic corticosteroids can suppress immune responses and may make infections harder to recognize. Contact a clinician if you develop fever, worsening illness, or known exposure to certain contagious infections. Vaccination decisions should be reviewed with a prescriber because immune response may be reduced and some live vaccines may be unsuitable during immunosuppressive corticosteroid treatment.
Monitor blood glucose more closely if you have diabetes or are at increased risk of diabetes.
Seek medical advice for marked swelling, rapid weight gain, shortness of breath, severe mood changes, or vision problems.
Discuss bone protection if treatment will be prolonged or repeated frequently.
Tell clinicians and dentists that you are taking or have recently taken systemic corticosteroids.
US Patient Perspectives and Common Challenges
Experiences Discussed by Patients
Discussions on Drugs.com, WebMD, PatientsLikeMe, Inspire, and condition-specific patient communities commonly reflect both the benefits and burdens associated with prednisone. People often discuss relief of inflammation alongside trouble sleeping, increased appetite, restlessness, or mood changes. These reports can help patients identify topics to raise with a clinician, but they cannot predict an individual's response or replace professional guidance.
Common Practical Challenges
Changing doses during a multi-step taper can be difficult to track. Other recurring concerns include fitting a morning dose into a changing work schedule, managing appetite, monitoring blood glucose, and distinguishing expected effects from symptoms that need prompt attention. A written dosing calendar and pharmacist counseling can be especially useful when different tablet strengths are combined.
Local Pharmacy Access and Available Options
Prednisone is commonly dispensed through US channels such as CVS Pharmacy, Walgreens, Walmart Pharmacy, Costco Pharmacy, independent community pharmacies, and licensed mail-order services. Availability, manufacturer, price, and strength can differ by location and cannot be assumed for an individual branch. State pharmacy rules also vary, while federal regulation and state licensing remain separate layers of oversight.
We currently list 5 mg tablets in quantities of 180, 270, and 360 pills. Our 10 mg, 20 mg, and 40 mg tablets are listed in quantities of 60, 90, 120, 180, 270, and 360 pills. These options should not be used to design a dose or taper without clinical direction.
Online Pharmacy Trends in the United States
Online pharmacy services can be useful for routine, non-urgent access, particularly for people who live far from a pharmacy, have limited transportation, or prefer to review package options privately. Long distances in rural areas and variable access across state lines make shipping time, state licensing, and product identification important considerations. Online access does not replace diagnosis, monitoring, or a prescriber's role in determining whether prednisone is appropriate.
Medicare, Insurance, and Private Payment
Coverage for prednisone depends on the specific Medicare Part D, Medicaid, employer, or commercial insurance plan and its formulary and pharmacy network. Coverage, eligibility, copays, and reimbursement cannot be inferred from the medicine name. The discontinued Deltasone branding may also be treated differently from generic prednisone. Customers comparing insurance and private-payment routes should check directly with their plan and pharmacy rather than assuming a particular benefit or price.
How Prednisone Works
Prednisone is a synthetic corticosteroid. After absorption, the liver converts it to prednisolone, which binds to glucocorticoid receptors and changes the activity of genes involved in inflammation and immune responses. This can reduce swelling, redness, and excessive immune activity. The same broad action also explains why prednisone can affect blood glucose, mood, sleep, infection risk, fluid balance, bones, eyes, and adrenal function.
Clinical Uses in US Practice
Prednisone is used for many corticosteroid-responsive inflammatory and immune-related conditions. Examples include severe allergic disorders, asthma exacerbations, rheumatoid arthritis and other rheumatic diseases, inflammatory bowel disease, certain skin disorders, and selected blood, kidney, lung, and autoimmune conditions. The appropriate dose and duration differ greatly by diagnosis and patient response. An acute asthma regimen, for example, is not interchangeable with long-term treatment for an autoimmune disease.
Prednisone is not a general-purpose pain reliever and should not be started for undiagnosed swelling, rash, breathing symptoms, or joint pain. It can mask infection and may worsen some untreated conditions, including systemic fungal infection.
Food, Drink, and Medicine Interactions
Taking prednisone with food may reduce stomach upset, but food does not eliminate medicine interactions. Nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen can increase the risk of gastrointestinal irritation, ulcers, or bleeding when used with corticosteroids. Prednisone can also affect blood glucose and may change the amount of insulin or other diabetes medicine needed.
Other potentially important interactions include certain diuretics, blood thinners, seizure medicines, antifungals, antibiotics, immune-suppressing treatments, and vaccines. The direction and clinical importance of an interaction can vary. Give the prescriber and pharmacist a complete list of prescription medicines, over-the-counter products, vitamins, and supplements before treatment begins.
Current Clinical Priorities
US clinical practice generally emphasizes using the lowest effective corticosteroid dose for the shortest duration consistent with controlling the condition. This does not mean every patient should receive a short course; some diseases require prolonged therapy. Rather, clinicians balance symptom control against cumulative risks and reassess whether the dose can be reduced or another treatment can limit systemic corticosteroid exposure.
Monitoring becomes more important with higher doses, repeated courses, or longer treatment. Depending on the patient, this may include blood pressure, blood glucose, weight, infection symptoms, bone health, eye health, growth in children, and signs of adrenal suppression.
Alternatives and Treatment Choice
Alternatives depend on the condition rather than on the Deltasone name. A prescriber may consider another systemic corticosteroid, such as methylprednisolone or dexamethasone, but these medicines differ in potency and duration and are not dose-for-dose substitutes. For asthma maintenance, inhaled corticosteroids may provide more localized treatment. Certain allergic symptoms may respond to an antihistamine, while inflammatory and autoimmune diseases may require disease-specific nonsteroid therapies.
Option
Potential role
Key consideration
Prednisone
Broad systemic treatment for corticosteroid-responsive conditions
Dose and schedule vary widely
Methylprednisolone
Systemic treatment for selected inflammatory conditions
Different potency and dosing
Inhaled corticosteroids
Long-term control of asthma and some lung conditions
Not a substitute for systemic treatment in every acute situation
Antihistamines
Selected allergic symptoms and itching
Do not replace prednisone when systemic corticosteroid treatment is clinically necessary
Regulatory and Prescription Context in the United States
Oral prednisone tablets are prescription-only medicines in the United States. Dispensing is governed by applicable federal requirements and state pharmacy laws. Deltasone is a discontinued US brand name, and that historical status does not by itself confirm the approval, manufacturer, or marketing status of a product currently listed under the name.
Our checkout does not require a prescription for this product. Under our ordering policy, customers may buy the listed prednisone tablets without submitting a prescription document at checkout. Our checkout requirement is separate from prednisone's prescription-only classification in the United States and does not change the need for appropriate clinical supervision.
Manufacturer-specific prescribing information may differ, so DailyMed should be consulted for the labeling associated with the actual manufacturer and strength supplied. Suspected serious adverse events or product-quality problems can be reported to the FDA MedWatch program.
Storage in US Household Conditions
Store the tablets at 68°F to 77°F; excursions are permitted between 59°F and 86°F. Keep the container tightly closed and protect it from moisture. In hot or humid parts of the United States, avoid cars, sun-facing windowsills, and steamy bathrooms. In regions with freezing winters, do not leave the container in an unheated garage, entryway, or outdoor mailbox for an extended period. Bring a delivered parcel indoors promptly and check the package if it has been exposed to unusual heat, cold, or moisture.
Delivery Across the United States
We offer two shipping methods for US addresses. Express shipping costs $29.99, includes tracking, and has an estimated delivery time of 4 to 7 days. Standard shipping costs $14.99, does not include tracking, and has an estimated delivery time of 14 to 21 days. Both methods may qualify for free shipping when the cart reaches the threshold displayed at our checkout. These time ranges are estimates rather than guarantees and may be affected by distance and last-mile conditions.
We accept Visa, Mastercard, American Express, Discover, Bitcoin, and USDT. Our support team is available 24/7 by email, online chat, and phone, and a pharmacist is available for medicine-related questions.
Deltasone Delivery Estimates to the United States
City
Express
Standard
Fort Worth
≈ 5 days
≈ 15 days
Denver
≈ 5 days
≈ 21 days
Los Angeles
≈ 6 days
≈ 14 days
Detroit
≈ 5 days
≈ 15 days
San Francisco
≈ 6 days
≈ 15 days
Estimated shipping times are based on our experience with previous deliveries and are not guaranteed delivery dates.
Deltasone: A US Summary
Deltasone is a discontinued US brand name that remains familiar as a reference to prednisone. The oral tablets listed here contain prednisone in 5 mg, 10 mg, 20 mg, and 40 mg strengths. Safe use depends on an individualized dose, attention to interactions and side effects, and careful adherence to any taper a prescriber establishes. Taking the medicine with food, using a consistent routine, and storing the tablets within the stated temperature range can support practical day-to-day use.
The bottle seal on my Deltasone package looks partly broken after delivery. Can I still use the tablets?
A
Answered by Support team
Do not use tablets from a package with a damaged seal until the issue has been checked. Keep the package and its labeling, and contact customer service within 7 days of delivery to arrange a replacement or refund.
Q
Asked by Daniel Ramirez, Phoenix, United States
I have type 2 diabetes and was prescribed prednisone for an inflammatory flare. Will it affect my blood sugar?
Yes. Prednisone can raise blood glucose and may increase the amount of insulin or other diabetes medicine needed. Check glucose more closely during treatment and discuss a monitoring and medication-adjustment plan with the clinician managing your diabetes.
Product specifications
Active ingredient
Prednisone
Drug class
Corticosteroid
Dosage form
Tablet
Available strengths
5 mg, 10 mg, 20 mg, 40 mg
Route
Oral
Storage
Store at 68°F to 77°F; excursions permitted between 59°F and 86°F. Keep the container tightly closed and protect from moisture.
ATC code
H02AB07
Regulatory information
Approval StatusPrednisone is fully approved for human therapeutic use in the United States.
Prescription RequirementsA valid prescription from an authorized healthcare professional is required to dispense these tablets.