Sildalis (Sildenafil 100 mg + Tadalafil 20 mg) Tablets

Sildalis
Generic:
Sildenafil and Tadalafil
Analogs:
Sildenafil Tadalafil Viagra Cialis Vardenafil Levitra Avanafil Stendra Spedra Alprostadil Caverject Muse Vitaros
Sildalis is a fixed-dose oral tablet pairing sildenafil 100 mg with tadalafil 20 mg, offered by us in package sizes from 10 to 360 pills for customers comparing dual-PDE5-inhibitor options.
In stock: 13 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Sildalis 100mg+20mg

Quantity Price per tablet You save Total price
10 C$7.42 - C$74.20
20 C$4.48 C$58.80 C$89.60
30 C$4.01 C$102.20 C$120.40
60 C$2.47 C$296.80 C$148.40
90 C$2.32 C$459.20 C$208.60
120 C$2.11 C$637.00 C$253.40
180 C$1.82 C$1,008.00 C$327.60
270 C$1.49 C$1,601.60 C$401.80
360 C$1.40 C$2,165.80 C$505.40

Manufacturers

RSM Enterprises Pvt. Ltd.

Payment & Shipping

Package Example

Your order is securely packed and usually ships within 24 hours. Here is what a typical parcel looks like.

It is about the size of a regular letter (24x11x0.7 cm) and does not show any details of what is inside.

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Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over C$420.00Estimated delivery to Canada: 4-7 days
Standard Free for orders over C$280.00Estimated delivery to Canada: 14-21 days
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Discount Coupons

  • Victoria Day - May 18, 2026 8% VICTORIA8
  • Canada Day - July 1, 2026 10% CANADADAY10
  • Labour Day - September 7, 2026 6% LABOUR6
  • Thanksgiving (Canada) - October 12, 2026 9% THANKS9
  • Boxing Day - December 26, 2026 12% BOXING12

FAQ

Not necessarily. Tablets with the same active ingredients may differ from a brand-name product in colour, shape, size, coating, and imprint, and we do not guarantee that the supplied tablets will match a brand-name appearance.

Description

Sildalis brings together two different erectile dysfunction ingredients - sildenafil 100 mg and tadalafil 20 mg - inside a single oral tablet. That single fact should shape how a customer compares it against other options in our catalogue. Instead of choosing between a sildenafil-only tablet such as Viagra or a tadalafil-only tablet such as Cialis, Sildalis layers both PDE5 inhibitors together at their higher single-agent strengths in one fixed dose. There is no way to take a smaller amount of one ingredient without the other, and no titration between the two. For anyone weighing a purchase decision, the practical consequence is straightforward: Sildalis is not a flexible, adjustable-dose product. It is a single fixed combination, and it deserves to be evaluated on that basis rather than measured strength-for-strength against a single-ingredient tablet.

What Sildalis actually is

Sildalis is the catalogue name we use for a tablet that supplies sildenafil 100 mg and tadalafil 20 mg per tablet, taken by mouth. Both ingredients belong to the same drug class, phosphodiesterase type 5 (PDE5) inhibitors, but they differ in how quickly they act and how long their effects last when used individually. Combining them in one tablet is a distinct product decision from offering either ingredient on its own, and we keep that distinction consistent everywhere we describe Sildalis: one tablet, one fixed strength pairing, taken orally.

Who might consider Sildalis tablets?

Sildalis is formulated for adult men experiencing erectile dysfunction. Because it fixes two PDE5 inhibitors into a single tablet rather than offering a range of individual doses, it presents a different and less flexible choice than a standard single-ingredient tablet. Before ordering, it helps to think through a short list of practical questions:

  • Have you already used a single-ingredient PDE5 inhibitor, such as sildenafil or tadalafil, and want to understand how a combined tablet differs, rather than assuming it is simply "stronger"?
  • Are you free of major PDE5 inhibitor contraindications, including nitrate use, and have cardiovascular conditions or a recent stroke or heart attack been assessed by a qualified health professional?
  • Do you understand that Sildalis is intended only for adult men and has no established role for women or children?
  • Are you prepared to discuss an unfamiliar fixed combination with a prescriber or pharmacist rather than relying on it without individualized guidance?

If any of these points raise doubts, a single-ingredient option such as Viagra or Cialis is usually the more transparent starting point, since dosing and effects for each ingredient are individually well characterized.

How Sildalis works, and what that means in practice

Both sildenafil and tadalafil work by inhibiting the PDE5 enzyme, which allows nitric oxide-driven relaxation of smooth muscle in the blood vessels of the penis to persist longer during sexual stimulation. The result is improved blood flow into the erectile tissue when arousal is present; neither ingredient creates arousal on its own. When used individually, sildenafil typically has a shorter activity window, while tadalafil remains active for considerably longer. Putting both into one tablet produces overlapping exposure to two medicines from the same class, which is meaningfully different from taking either ingredient alone.

Step-by-Step Mechanism of Action

Because the diagram traces both pathways side by side, it also illustrates why the two effects should not be interpreted as "double the benefit." Vasodilation from two PDE5 inhibitors acting together may produce additive blood-pressure-lowering effects. Official tadalafil guidance states that combination with other PDE5 inhibitors has not been studied and is not recommended.

How to approach use and build a safe routine

There is no established authorized dosing regimen for this fixed sildenafil-tadalafil combination in Canada, so the usual dosing instructions for either ingredient alone should not be transferred to Sildalis. In particular, it should not be assumed that one tablet is an appropriate dose or that the dose can safely be repeated according to a standard sildenafil or tadalafil schedule. Individualized directions should come from a qualified prescriber who has reviewed other medicines, blood pressure, cardiovascular health, and previous reactions to PDE5 inhibitors.

If use has been specifically directed by a health professional, remember that each tablet already contains both ingredients. Do not add Viagra, Cialis, Levitra, another sildenafil or tadalafil product, or any other PDE5 inhibitor. A heavy, high-fat meal can delay absorption of the sildenafil component, while larger amounts of alcohol can add to dizziness and blood-pressure lowering. Because tadalafil remains in the body longer than sildenafil, interaction risk can continue after the initial effects are no longer noticeable.

Available strength and package sizes

We offer Sildalis in one fixed strength - 100 mg sildenafil combined with 20 mg tadalafil per tablet - and count the offer by pills rather than by a bundled course length. The currently available package quantities are 10, 20, 30, 60, 90, 120, 180, 270, and 360 pills:

  • Smaller packs contain 10, 20, or 30 pills.
  • Mid-range packs contain 60, 90, or 120 pills.
  • Larger packs contain 180, 270, or 360 pills.

Every package contains the identical 100 mg + 20 mg tablet. A larger pack changes only the pill count, not the strength or formulation.

How soon might the ingredients act, and how long might effects last?

No reliable onset or duration has been established for the Sildalis fixed combination. When sildenafil is used on its own, it commonly begins to act within about 30 to 60 minutes, and a high-fat meal may delay that onset. Tadalafil used on its own has a longer potential activity window, lasting up to 36 hours in some patients. These single-ingredient timings cannot be added together or treated as a tested prediction for Sildalis.

The practical point is that effects and adverse reactions may overlap, while tadalafil-related interaction risk can persist longer than the more noticeable sildenafil window. Sexual stimulation is still required for an erectile response, and neither ingredient guarantees a particular result or timing.

Important safety priorities

Sildalis carries the safety concerns associated with both sildenafil and tadalafil, with the added potential for overlapping vasodilatory effects:

  • Never combine Sildalis with nitrate medicines, including short-acting nitroglycerin, or recreational nitrite drugs known as "poppers," because the combination can cause a dangerous drop in blood pressure.
  • Do not combine it with soluble guanylate cyclase stimulators such as riociguat, which can also produce severe hypotension.
  • People with unstable angina, uncontrolled low blood pressure, or a recent heart attack or stroke need medical assessment because sexual activity or PDE5 inhibitor exposure may be inadvisable.
  • Do not take Sildalis with any other PDE5 inhibitor - including Viagra, Cialis, or Levitra - since Sildalis already supplies two PDE5 inhibitors.
  • Sildalis is not intended for women, including during pregnancy or breastfeeding, and has no established paediatric use.
  • Seek urgent medical attention for an erection lasting more than four hours or for sudden vision or hearing changes.

Common effects associated with sildenafil or tadalafil include headache, flushing, indigestion, nasal congestion, dizziness, and visual disturbance. Tadalafil can also cause back or muscle pain. The sildenafil-tadalafil active-ingredient combination is not authorized for human medicinal use in Canada, although sildenafil and tadalafil are each used in separately authorized single-ingredient medicines.

Interactions and practical precautions

Beyond nitrates, riociguat, and other PDE5 inhibitors, several additional interactions are worth planning around:

  • Alpha-blocker medicines used for blood pressure or prostate symptoms can compound the blood-pressure-lowering effect of PDE5 inhibitors; combined use requires professional guidance on dose, stability, and timing.
  • Other blood-pressure medicines may increase the chance of dizziness or symptomatic hypotension, particularly when combined with alcohol or dehydration.
  • Grapefruit and grapefruit juice can raise blood levels of sildenafil and tadalafil by affecting CYP3A4 metabolism, potentially increasing adverse effects.
  • Certain HIV protease inhibitors, macrolide antibiotics, and azole antifungal medicines can also raise PDE5 inhibitor levels and may require avoidance or dose adjustment when an individual PDE5 inhibitor is prescribed.
  • Strong enzyme inducers, including rifampin and some antiseizure medicines, may reduce ingredient exposure and make effects less predictable.

Dizziness and visual effects can impair driving or operating machinery. Anyone affected should avoid those activities until the symptoms have fully resolved.

Sildalis and Viagra: fixed combination or single ingredient?

Comparison: Sildalis and Viagra

FeatureSildalisViagra
Active ingredient(s)Sildenafil and tadalafilSildenafil citrate
Pharmacological classDual PDE5 inhibitorsSingle PDE5 inhibitor
Dosage formTabletTablet
Available strengths100 mg sildenafil + 20 mg tadalafil25 mg, 50 mg, 100 mg sildenafil
Primary indicationTreatment of erectile dysfunctionTreatment of erectile dysfunction
Overview of key pharmacological and formulation differences.

The comparison above sets Sildalis, our fixed sildenafil-tadalafil tablet, against Viagra, our sildenafil-only tablet. Viagra may suit a customer who wants a single, individually studied ingredient with a well-documented dosing history and a shorter, more predictable window of activity. Sildalis pairs shorter-acting sildenafil and longer-acting tadalafil in one tablet, but that pairing has not been evaluated in the same way as each ingredient on its own and is not recommended by official guidance on combining PDE5 inhibitors.

Cialis, our tadalafil-only tablet, is relevant for the same reason: anyone interested mainly in a longer tadalafil-driven activity window may find that a tadalafil-only medicine offers that characteristic with a simpler, single-ingredient profile. Readers weighing these differences can browse our erectile dysfunction treatments and compare Viagra or Cialis with Sildalis.

Do we require a prescription for Sildalis in Canada?

Medicine prescription status and our ordering requirements are separate matters. Authorized oral sildenafil and tadalafil medicines for erectile dysfunction are prescription medicines in Canada. Separately, our ordering policy does not require a customer to submit a prescription for us to accept an order for Sildalis. This describes our checkout process and does not change the medical or regulatory status of the medicines involved.

Because Sildalis combines two PDE5 inhibitors at high single-agent strengths, obtaining advice from a qualified prescriber or pharmacist remains a sensible safety step even though our checkout does not require prescription submission.

Ordering, delivery, and receiving your order

We have operated as an online pharmacy catalogue since 2017, and our support team is available 24/7 by email, online chat, and phone, with a pharmacist available to answer product questions before or after an order. Ordering Sildalis follows the same straightforward process as our other listings:

  • Choose a package of 10, 20, 30, 60, 90, 120, 180, 270, or 360 pills, all at the same 100 mg sildenafil + 20 mg tadalafil strength.
  • Complete checkout in Canadian dollars using our supported payment methods.
  • Provide a delivery address in Canada; we pack and dispatch orders promptly and provide an estimated delivery window at checkout.
  • Contact our support team at any time if a question comes up before your order arrives.

We treat any delivery estimate as exactly that - an estimate - because actual transit time can vary after an order leaves our hands. Once received, store the tablets at room temperature between 20°C and 25°C, away from moisture, heat, and direct light.

Making the decision

Choosing between Sildalis and a single-ingredient tablet comes down to a central trade-off: Sildalis places shorter-acting sildenafil and longer-acting tadalafil in one non-adjustable tablet, while sildenafil-only or tadalafil-only products have more conventional and individually documented dosing and safety profiles. The combined format should not be assumed to provide greater benefit, and its potential for overlapping adverse effects and interactions is an important part of the decision.

For customers who have reviewed those distinctions, we present the practical offer clearly: one 100 mg + 20 mg strength, nine package quantities, prices in CAD, and our ordering and delivery process. A health professional can help determine whether any PDE5 inhibitor is appropriate in light of cardiovascular health, other medicines, and previous treatment experience.

Medically reviewed by
Mildred Torres
Pharmacist
Updated September 6, 2026

Product specifications

Active ingredientSildenafil and tadalafil
Drug classPhosphodiesterase type 5 (PDE5) inhibitors
Dosage formTablet
Available strengths100 mg sildenafil + 20 mg tadalafil
RouteOral
StorageStore at room temperature between 20°C and 25°C, away from moisture, heat, and light.

Regulatory information

Authorization statusHealth Canada has not authorized the combination of sildenafil and tadalafil for human use.

More information