Motilium (Domperidone) 10 mg Film-Coated Tablets

Motilium is the branded film-coated tablet form of domperidone, an oral antiemetic used to relieve nausea and vomiting. We carry it in a single 10 mg strength and offer package sizes from 10 up to 360 tablets, so the main decision for most customers is simply matching the pack quantity to the course length a prescriber has recommended, then confirming how we handle prescriptions and delivery before checkout.

How Domperidone Works and When It Helps

Domperidone blocks dopamine D2 receptors in the gut wall and in the chemoreceptor trigger zone, an area of the brainstem that lies largely outside the blood-brain barrier. Because domperidone crosses into the central nervous system only to a limited extent, it tends to cause less drowsiness and fewer movement-related side effects than an older dopamine antagonist such as metoclopramide, while still reducing nausea and vomiting signals and encouraging the stomach to empty more efficiently. Tablets are generally taken before meals because food can delay their absorption. Domperidone is absorbed relatively quickly, although the timing and degree of symptom relief vary between individuals.

Usual Dosing and Timing

The established adult approach is 10 mg taken up to three times a day before meals, using the lowest dose that controls symptoms for the shortest practical time. Regulatory guidance in Canada caps the usual daily total at 30 mg, since doses above that threshold materially increase cardiac risk. Treatment is typically reassessed after about a week rather than continued indefinitely. The fixed 10 mg tablet strength we carry is designed for adult use; children require weight-based dosing around 0.25 mg per kilogram per dose under a clinician's direction, which this tablet strength cannot reliably provide for smaller children. Nothing here replaces the specific regimen a prescriber sets for an individual customer.

Who Should Take Extra Care

Domperidone carries a recognized risk of serious ventricular arrhythmia and sudden cardiac death. The risk rises with daily doses above 30 mg, in people over 60, and in those with cardiac disease, significant electrolyte disturbances, an existing prolonged QT interval, or interacting medicines. It is not suitable for anyone with known hypersensitivity to domperidone, a prolactin-releasing pituitary tumour, moderate or severe hepatic impairment, or a condition where stimulating gut motility could be harmful, such as gastrointestinal bleeding, mechanical obstruction, or perforation. Pregnancy data are limited, so use in pregnancy is reserved for situations where a clinician judges that the benefit justifies the risk. Canadian guidance does not recommend domperidone for nursing women, and Health Canada has warned against its off-label use to increase breast milk supply because of the risk of QT prolongation and serious arrhythmia.

Side Effects and Interactions to Review

Possible side effects include dry mouth, headache, abdominal cramps, diarrhea, dizziness, and drowsiness. Domperidone can also raise prolactin levels, sometimes causing breast tenderness, milk discharge, or menstrual changes. Rare movement-related reactions can occur, particularly in younger patients. Before taking it, review all medicines and supplements with a healthcare professional. Strong CYP3A4 inhibitors and medicines that prolong the QT interval can raise domperidone exposure or compound its cardiac effects; examples include certain azole antifungals, macrolide antibiotics, HIV medicines, antiarrhythmics, antipsychotics, and antidepressants. Driving or operating machinery may be impaired until the individual response is known.

Strengths, Package Sizes, and Choosing Your Quantity

We list Motilium only as 10 mg film-coated tablets for oral use, matching the brand's standard formulation, and we offer that single strength across nine pack sizes so customers can order close to the quantity their prescribed course requires rather than over-buying.

These duration examples are for quantity comparison only. A pack may last longer if the prescribed frequency is lower, and a larger pack does not mean that prolonged treatment is appropriate. Compare the tablet count with your written directions, planned review date, and current supply before ordering.

Whatever size you choose, the tablet strength and film coating stay identical across every pack; only the total tablet count changes, which keeps dosing straightforward regardless of the quantity ordered.

Ordering Motilium Through Our Pharmacy

Domperidone is classified as a prescription medicine in Canada and ordinarily requires a prescription from an authorized prescriber. That classification describes the medicine's status in Canada. Separately, our ordering policy does not require customers to upload a prescription for us to accept an order, so that step does not block checkout. We still recommend having appropriate medical guidance, given the cardiac risks and interaction considerations described above. Our pharmacist team is available 24/7 by email, online chat, or phone if questions come up before or after you order.

Before checkout, confirm that you have selected the 10 mg strength, the intended tablet quantity, the correct delivery address and postal code, and a suitable shipping option. Larger packs may offer convenience, but they should not be chosen solely for value when treatment is expected to be brief or reviewed frequently.

We ship across Canada with a choice between tracked Express shipping and a slower Standard option, and every listed pack size from 10 to 360 tablets can be selected at checkout along with your preferred payment method. If nausea is one of several digestive symptoms you're managing, our Gastrointestinal Tract category brings together related treatments worth comparing.

Storage, Delivery Checks, and Everyday Use

Store Motilium tablets below 30°C in their original packaging, away from direct light and moisture, to preserve the medicine until the labelled expiry date. When your order arrives, check that the package label shows Motilium, domperidone, 10 mg, and film-coated tablets. Confirm that the tablet count matches what you ordered and that the packaging and expiry information are intact before taking the medicine.

Take each dose before a meal as directed, keep to the lowest effective dose for the shortest reasonable period, and do not exceed a 30 mg daily total unless a qualified healthcare professional has specifically directed otherwise. If you experience a fast or irregular heartbeat, fainting, or severe dizziness, stop taking domperidone and seek urgent medical attention. Contact a healthcare professional promptly about unusual muscle movements or other concerning effects. Our support team is available around the clock if you have questions about your order, pack size, storage, or the supplied product information.