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Cafergot

Cafergot (Cafatine, Cafergot, Cafetrate, Ercaf, Migergot, Wigraine)

Generic name: caffeine Ergotamine

Brand names: Cafatine, Cafergot, Cafetrate, Ercaf, Migergot, Wigraine

Pharmacological Effects:

Combined medication. Ergotamine – natural ergot alkaloids, increases the tone of extended extracranial arteries, affects on the serotonin receptors. Caffeine accelerates and increases the absorption of ergotamine.

Indications:

The headache of vascular origin (including migraine).

Contraindications:

Hypersensitivity, obliterating peripheral arterial disease, lactation, arterial hypertension, coronary heart disease, liver failure, sepsis, chronic renal failure, pregnancy.

Side effects:

Nausea, vomiting, increased blood pressure, allergic reactions. If prolonged use – false angina, weakness and pain in the limbs, tachycardia, fibrous changes of the pleura and retroperitoneum, tremor, bradycardia. Overdosage. Symptoms: paresthesia, tachycardia, drowsiness, depression of the respiratory center, confusion, coma, dizziness. Treatment: activated charcoal, gastric lavage, symptomatic therapy.

Cafergot

Dosage:

Inside. Is taken early in the attack, 2 tablets, if needed – 1 tablet at intervals of 30 min to improve the state, not exceeding the maximum daily dose (6 tablets). Maximum weekly dose – 10 tablets. If subsequent attacks, the initial dose increased to 3 tablets, depending on the total dose that has been taken during previous attacks.

Cautions:

Not used for prophylaxis of migraine.

Interaction:

Macrolides increase the concentration of ergotamine. Alpha-adrenostimulating drugs, propranolol, nicotine increase vasoconstriction demonstrated action.

Storage:

In a dry place with temperature under 30 C

Warning:

Before taking the drug you should consult with your doctor.

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