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Last updated on November 21st, 2021

Cafergot (Cafatine, Cafergot, Cafetrate, Ercaf, Migergot, Wigraine)

Generic name: caffeine Ergotamine

Brand names: Cafatine, Cafergot, Cafetrate, Ercaf, Migergot, Wigraine

Pharmacological Effects:

Combined medication. Ergotamine – natural ergot alkaloids, increases the tone of extended extracranial arteries, affects on the serotonin receptors. Caffeine accelerates and increases the absorption of ergotamine.


The headache of vascular origin (including migraine).


Hypersensitivity, obliterating peripheral arterial disease, lactation, arterial hypertension, coronary heart disease, liver failure, sepsis, chronic renal failure, pregnancy.

Side effects:

Nausea, vomiting, increased blood pressure, allergic reactions. If prolonged use – false angina, weakness and pain in the limbs, tachycardia, fibrous changes of the pleura and retroperitoneum, tremor, bradycardia. Overdosage.


paresthesia, tachycardia, drowsiness, depression of the respiratory center, confusion, coma, dizziness.


activated charcoal, gastric lavage, symptomatic therapy.



Inside. Is taken early in the attack, 2 tablets, if needed – 1 tablet at intervals of 30 min to improve the state, not exceeding the maximum daily dose (6 tablets). Maximum weekly dose – 10 tablets. If subsequent attacks, the initial dose increased to 3 tablets, depending on the total dose that has been taken during previous attacks.


Not used for prophylaxis of migraine.


Macrolides increase the concentration of ergotamine. Alpha-adrenostimulating drugs, propranolol, nicotine increase vasoconstriction demonstrated action.


In a dry place with temperature under 30 C

Warning: Before taking the drug you should consult with your doctor.

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