Abilify (Aripiprazole, Abilitat, Arizol, Arlemide, Brisking, Ilimit, Irazem)
Generic name: Aripiprazole
Brand names: Aripiprazole, Abilitat, Arizol, Arlemide, Brisking, Ilimit, Irazem
How does this medicine work?
The medicine has a high affinity in vitro to D 2 and D 3 dopamine receptors, 5HT 1a and 5HT 2a serotonin receptors and moderate affinity for dopamine D 4, 5HT 2c, and 5HT 7 serotonin,? 1-adrenergic and H 1 histamine receptor. Abilify is characterized by moderate affinity for serotonin reuptake sites and the lack of affinity for muscarinic receptors. The medicine in experiments on animals showed antagonism against dopaminergic hyperactivity and dopaminergic agonism against gipoaktivnosti.
When do I need to take the drug?
The medicine is taken for the recovery of acute episodes of schizophrenia and for maintenance therapy.
The medicine is prescribed for the treatment of acute manic aspects of bipolar disorder type I and for maintenance therapy in patients with bipolar disorder type I, not so long ago suffered manic or mixed moment.
Contraindications
– Augmented sensitivity to aripiprazole or any other component that is part of the substance
– Breastfeeding when using the substance is not recommended
– Age under 18 years
– Adequate and properly controlled research was not conducted in pregnant women
Dosage
Schizophrenia: it’s recommended to take Abilify in the initial dose of 10 or 15 mg 1 per day, without regard to meals. Supporting dose – 15 mg / day. In clinical conditions doses are ranging from 10 to 30 mg / day.
Manic moments in bipolar disorder. The medicine need to be taken regardless of the meal, starting with doses of 15 or 30 mg / day. Changing the dose, if nessecary must be carried out with an interval of at least 24 h.
Side effects
- Sore throat,
- stiffness in the throat,
- heat stroke,
- photosensitivity,
- oral pain,
- heavy-headedness,
- chills,
- face edema,
- pain in the pelvis,
- swelling stomach,
- Mendelson syndrome,
- peripheral edema,
- tension in the chest,
- chest pain in the neck,
- stiff jaw,
- stiffness in the back,
- candidiasis,
- flu-like syndrome,
- malaise.
Storage:
To keep in dark place at a temperature not exceeding 25 ° C.
Warning:
Before taking the drug you need to consult your doctor.
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