Pharmacopoeias. In China, Europe, Japan, US. Some pharmacopoeias include a single monograph that permits both the light and heavy varieties while some have 2 separate monographs for the 2 varieties.
European Pharmacopoeia, 6th ed. (Magnesium Carbonate, Heavy Magnesii Subcarbonas Ponderosus). A hydrated basic magnesium carbonate containing the equivalent of 40 to 45% of MgO. A white or almost white powder. 15 ghas an apparent volume before settling of not more than 60 mL. Practically insoluble in water dissolves in dilute acids with strong effervescence.
European Pharmacopoeia, 6th ed. (Magnesium Carbonate, Light Magnesii Subcarbonas Levis). A hydrated basic magnesium carbonate containing the equivalent of 40 to 45% of MgO. A white or almost white powder. 15 g has an apparent volume before settling of at least 100 mL. Practically insoluble in water dissolves in dilute acids with strong effervescence.
The United States Pharmacopeia 31, 2008 (Magnesium Carbonate). A basic hydrated magnesium carbonate or a normal hydrated magnesium carbonate containing the equivalent of 40.0 to 43.5% of MgO. It is an odourless, bulky white powder or light, white, friable masses. Practically insoluble in water insoluble in alcohol dissolves in dilute acids with effervescence.
Magnesium carbonate is an antacid with general properties similar to those of magnesium hydroxide (below) that is given in oral doses of up to about 500 mg. When given orally, it reacts with gastric acid to form soluble magnesium chloride and carbon dioxide in the stomach the carbon dioxide may cause flatulence and eructation. Magnesium carbonate is often given with aluminium-containing antacids such as aluminium hydroxide, which counteract its laxative effect.
Magnesium carbonate may be used as a magnesium supplement. It is also used as a food additive.
BP 2008: Aromatic Magnesium Carbonate Mixture; Compound Magnesium Trisilicate Oral Powder Kaolin Mixture; Magnesium Sulphate Mixture; Magnesium Trisilicate Mixture
The United States Pharmacopeia 31, 2008: Alumina and Magnesium Carbonate Oral Suspension; Alumina and Magnesium Carbonate Tablets; Alumina, Magnesium Carbonate, and Magnesium Oxide Tablets; Calcium and Magnesium Carbonates Oral Suspension; Calcium and Magnesium Carbonates Tablets; Magnesium Carbonate and Citric Acid for Oral Solution; Magnesium Carbonate and Sodium Bicarbonate for Oral Suspension; Magnesium Carbonate, Citric Acid, and Potassium Citrate for Oral Solution; Magnesium Citrate Oral Solution.
Argentina: Polvo Roge
France: Mag 2; Mag 2 Junior; Sargemag
Germany: Biolectra Magnesium 365; Palmicol
Greece: Limonata Citromagnes
Poland: Additiva Magnesium; Magnezin
South Africa: Be-Lax
Switzerland: Magnesium Nutrimed
Used as an adjunct in:
Argentina: Bufferin; Dristan Analgesico; Dristan Compuesto
Brazil: Bufferin; Somalgin
Canada: Aspirin with Stomach Guard; Bufferin; Tri-Buffered ASA
USA: Adprin-B; Bufferin; Buffex; Extra Strength Bayer Plus.