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Last updated on November 17th, 2021

Synonyms: Amerikinių šaltekšnių žievė; Cáscara sagrada; Cascararinde; Chittem Bark; Kůra řešetláku Purshova; Kaszkarabokor kéreg; Rhamni Purshianae Cortex; Rhamni Purshiani Cortex; Sacred Bark; Sagradabark; Sagradankuori
CAS: 8047-27-6; 8015-89-2 (cascara sagrada extract)
ATC code: A06AB07
Read code: y01Rc

Pharmacopoeias. InEurope and US.

European Pharmacopoeia, 6th ed. (Cascara). The dried, whole or fragmented bark of Rhamnus purshianus (= Frangula purshiana). It contains not less than 8.0% of hydroxyanthracene glycosides of which not less than 60% consists of cascarosides, both expressed as cascaroside A (C27H32014 = 580.5). and calculated with reference to the dried drug. Protect from light.

The United States Pharmacopeia 31, 2008 (Cascara Sagrada). The dried bark of Rhamnus purshianus (Rhamnaceae). It contains not less than 7% of total hydroxyanthracene derivatives calculated on the dried basis, of which not less than 60% consists of cascarosides, both calculated as cascaroside A. It has a distinct odour.



Cascara is an anthraquinone stimulant laxative with general properties similar to those of senna. It has been used in the treatment of constipation in oral doses equivalent to about 20 mg of total hydroxyanthracene derivatives daily.

Breast feeding.

No adverse effects have been seen in breastfed infants whose mothers were receiving cascara, and the American Academy of Pediatrics considers that it is therefore usually compatible with breast feeding.


British Pharmacopoeia 2008: Cascara Dry Extract Cascara Tablets

The United States Pharmacopeia 31, 2008: Aromatic Cascara Fluidextract Cascara Sagrada Extract Cascara

Sagrada Fluidextract Cascara Tablets.

Proprietary Preparations

Argentina: Natulax

Brazil: Laxsotrin

France: Peristaltine

Germany: Legapas Port Laxolen


Argentina: Bilidren Calculina † Cascara Sagrada Bouzen † Cascara Sagrada Oligoplex Cascara Sagrada Puler † Veracolate Yuyo

Australia: Colax Peritone

Austria: Cascara-Salax Dragees Neunzehn † Silberne

Belgium: Grains de Vals Vethoine

Brazil: BilifeF † Boldopeptan † Chofranina Composto Emagrecedor † Emagrevit † Eparemajurubilenof Pilulas De Witt’s-P Prisoventril † Solvobil Ventre Livre

Canada: Bicholate Cholasyn II Cholasyn-P Control Doulax Extra Strong Formula 12 † Herbal Laxative Herbal Laxative plus Yogurt Herbal Laxative † Herbalax † Herbolax Herborex Laxaco Laxative † Mucinum † Thunas Laxative †

Chile: Bulgarolax

France: Dragees Fuca Dragees Vegetales Rex Grains de Vals Imegul † Mucinum a I’Extrait de Cascara

Hong Kong: Mucinum Cascara †

Italy: Amaro Medicinale Coladren Combilax Confetti Lassativi CM Critichol Digelax † Dis-Cinil Complex Draverex Eparema Eparema-Levul Eupatol Fave di Fuca Grani di Vals Hepatos Hepatos BI2 Lassatina † Magisbile † Mepalax Schias-Amaro Medicinale † Solvobil Stimolfit Vadolax †

Norway: Cosylan

Portugal: Caroid † Mucinum

South Africa: Moultons Herbal Extract Veracolate †

Spain: Crislaxo Lipograsil Menabil Complex † Nico Hepatocyn Pildoras Zeninas

Sweden: Emulax

Switzerland: Padma-Lax Padmed Laxan

Thailand: Flatulence Hemolax Veracolate

UK: Dual-Lax Extra Strong Dual-Lax Normal Strength Jacksons Herbal Laxative Laxative Tablets Modern Herbals Laxative Modern Herbals Pile Natural Herb Tablets Out-of-Sorts Pileabs Piletabs Rhuaka Senokot Dual Relief Skin Eruptions Mixture

USA: Concentrated Milk of Magnesia-Cascara

Venezuela: Gameral

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