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Last updated on November 17th, 2021

Generic name: Labetalol

Brand name: Trandate

General Information:

Trandate is beta-blocker. This drug is prescribed to heal high blood pressure.

Your doctor may prescribe this remedy for other purposes. Contact your physician if you need to learn more information about this drug.

Don’t stop treatment with Trandate earlier than it was prescribed by your doctor even if you notice improvements of your condition. Stopping the medication too early may worsen your condition. Be careful about doing dangerous tasks, driving, operating machinery or climbing until you are aware how this drug affects you. Don’t drink alcohol. Always contact a medic before giving Trandate to a child.

What symptoms or conditions should I report to a doctor before I take this medicine?

It is important to report to a doctor if you have or had the following conditions:

  •     an unusual or allergic reaction to Trandate, other dyes, medicines, foods or preservatives
  •     diabetes
  •     bronchitis, asthma, emphysema
  •     a thyroid disorder
  •     pheochromocytoma
  •     low blood pressure
  •     depression
  •     a heart problem (heart block, slow heart rate, sick sinus syndrome, or congestive heart failure)
  •     myasthenia gravis
  •     liver or kidney disease
  •     problems with circulation (such as Raynaud’s syndrome)

How do I take this medicine?

Note: This remedy was prescribed to you only. Don’t share this medicament with others. Follow strictly your doctor’s recommendations. Don’t take more or longer than your doctor recommended.

Trandate is taken orally. Don’t take your drug more often than prescribed.


Taking any medicine in large doses you can have serious consequences for your health. If you feel an overdose, contact your health care professional instantly.

In large doses, this remedy may cause the following conditions:

  • uneven heartbeats
  • bluish-colored fingernails
  • shortness of breath
  • weakness
  • fainting
  • seizure (convulsions)
  • dizziness

If you forget about a dose:

In case you forgot to take the dose, take it at your earliest opportunity. Never double your dose if it is almost time for your next dose. Take only one dose at once.


  • guanabenz (Wytensin)
  • a heart medication: reserpine (Serpasil), nifedipine (Adalat, Procardia), diltiazem (Cardizem, Cartia), verapamil (Verelan, Calan, Isoptin)
  • clonidine (Catapres)
  • a diabetes medication: glyburide (Micronase, Diabeta, Glynase), insulin, chlorpropamide (Diabinese), glipizide (Glucotrol), or metformin (Glucophage)
  • allergy treatments (or if you are undergoing allergy skin-testing)
  • cold medicines, diet pills, stimulant medicines
  • an MAO inhibitor such as tranylcypromine (Parnate), isocarboxazid (Marplan), selegiline (Emsam, Eldepryl), phenelzine (Nardil),
  • medicine for asthma or other breathing disorders: bitolterol (Tornalate), albuterol (Proventil, Ventolin), pirbuterol (Maxair), metaproterenol (Alupent), theophylline (Theolair, Theo-Dur), terbutaline (Brethine, Brethaire, Bricanyl)

This list of interactions may be not complete. Provide your medical practitioners entire list of medicines, herbs, dietary supplements or non-prescription drugs you take. Moreover tell them whether you drink alcohol, use illegal drugs or smoke. Particular items may interact with your drug.

Side Effects:

Contact your physician immediately if you notice any of the following

Serious side effects:

  • allergy like skin rash, swelling of the face, lips, tongue, hives, itching, difficulty breathing
  • swelling of your feet or ankles
  • depression
  • fainting
  • slow or uneven heartbeats
  • nausea
  • feeling light-headed
  • stomach pain
  • feeling short of breath, even with mild exertion
  • loss of appetite
  • clay-colored stools
  • low fever.
  • jaundice (yellowing of the skin or eyes)
  • dark urine
  • cold feeling in your hands and feet

Less serious side effects:

  • tired feeling
  • sleep problems (insomnia)
  • decreased sex drive, impotence, or difficulty having an orgasm
  • anxiety, nervousness

This list of side effects may be not complete, others may occur. Inform your medical practitioners about all side effects you experience.

Important Information:

FDA pregnancy category C. Talk to your doctor if you are pregnant, breast-feeding or trying to get pregnant. Check your blood pressure on a regular basis. If you are going to have surgery, inform your  surgeon that you are taking Trandate. Avoid standing or sitting up quickly, especially if you are an older patient. Trandate is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.


Trandate should be stored at room temperature, in a tightly closed container. Protect from moisture, direct heat, and light. Do not store in the bathroom or near a sink. Keep Trandate out of the reach of children and away from animals.

Warning: Before taking the drug you need to consult your doctor. The information contained in this article is not intended to cover all possible precautions, drug interactions, adverse effects, directions, uses, allergic reactions or warnings.

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