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Actoplus met

Last updated on November 21st, 2021

Generic name: Metformin And Pioglitazone

Brand name: Actoplus Met

General Information:

Actoplus Met is a well-known antidiabetic medicament. It is a composite of two widely used ingredients: pioglitazone HCl and metformin. Actoplus Met is prescribed for people with type 2 diabetes who don’t use daily insulin injections type 2 diabetes (non-insulin dependent). It is taken in combination with exercise, weight reduction and diet. It works by controlling blood glucose.

This drug can be used for extra goals; consult your physician if you need more detailed information.

What should I report to a doctor before I take this medicine?

Your health care providers need to know if you have any of the following conditions:

  •     liver or kidney disease
  •     diabetic ketoacidosis
  •     allergy to Actoplus Met, dyes, medicines, foods or preservatives
  •     polycystic ovary syndrome
  •     high acid levels in blood
  •     heart disease or congestive heart failure
  •     vomiting
  •     eye problems
  •     serious infection or injury
  •     anemia
  •     a history of heart attack or stroke
  •     insulin-dependent diabetes
  •     pregnancy, breastfeeding or planning to become pregnant

How to take Actoplus Met:

Actoplus Met is recommended to take orally usually once or twice daily with food, or as directed by your medical practitioner. Dosages above 45 mg of pioglitazone per day, or 2550 mg of metformin per day are not recommended. Take the doses on the rigid schedule. Don’t take your medicament more often than directed. Never stop taking unless given advice of your doctor or health care professional.

Consult your pediatrician concerning the use of this drug in children. Peculiar care may be required.



Overdose symptoms may include feeling light-headed, irritability, muscle pain, shortness of breath, cold feeling, seizure (convulsions), dizziness, sweating, fast heartbeat, headache, weakness, stomach pain, fainting, confusion, tremors, hunger, fainting and drowsiness. In case you suppose you have taken too much of this medicine, contact an emergency room or a poison control center at once.

Note: This medicament is exclusively for you. Never share {this medication with anyone.

If you miss a dose:

If you forget about the dose, try to take it as soon as you have the opportunity. If the time for the next dose has come, take only that dose. Never take the dose twice or redundant doses.

What drugs may this medicament interact with:

  •     Birth control
  •     Furosemide
  •     Nifedipine
  •     Thiazides
  •     Diruetics
  •     Corticosteroids
  •     Calcium blockers
  •     Phenothiazines
  •     Nicotinic acid
  •     Thyroid medicines
  •     Phenytoin
  •     Sympathomimetics
  •     Isoniazid

This list may not describe all existing interactions. Provide your medics entire list of medications, herbs, dietary supplements or non-prescription drugs you use. Moreover tell them if you use illegal drugs, drink alcohol or smoke. Particular components can interfere with your drug.


What side effects may I observe from this medicament?

Side effects that you should inform your medical practitioner as quickly as possible:

  •     rapid weight gain
  •     jaundice (yellowing of your skin or eyes)
  •     unusual bleeding or bruising
  •     swelling of the hands, legs, or feet
  •     low blood sugar
  •     chills, fever, flu symptoms, body aches
  •     feeling short of breath, even with mild exertion
  •     sharp pain in your upper stomach (especially after eating)
  •     eye pain, blurred vision, or seeing halos around lights
  •     pain or burning when you urinate (dark urine)
  •     allergy like skin rash, swelling of the face, lips, tongue, hives, itching, difficulty breathing
  •     appetite loss

Side effects which usually don’t need medical control

(ask your medical practitioner if they last or become troubling):

  • unpleasant , unusual taste in your mouth
  • spinning sensation, dizziness
  • muscle or joint pain
  • upset stomach, vomiting, nausea, stomach pain, constipation, diarrhea
  • mild skin rash
  • heartburn
  • blurred vision
  • cold symptoms or cough
  • tired feeling, drowsiness
  • numbness or tingly feeling

The list of Side effects may be not complete.

Important Information:

Some people have developed a life-threatening condition called lactic acidosis while taking Actoplus Met. Early signs of lactic acidosis generally get worse over time and this condition can be fatal.

This medication is not recommended for use during pregnancy. Most experts agree that insulin is the best treatment for pregnant women with diabetes. Inquire your medic for more details and follow all instructions carefully.

You may get dizzy or drowsy. Don’t use machinery, drive or do any activity that requires mental sharpness until you know the way this medicine affects you.

Avoid standing or sitting up quickly, moreover if you are an older patient. This decreases the dizzy or fainting spells risk.

Limit alcoholic beverages while taking this medication because it can increase your risk of developing low blood sugar (hypoglycemia).

How should I save this drug?

Keep away from children. Store at room temperature about 15 and 30 degrees C (59 and 86 degrees F). Keep your medicine container tightly closed and protect from moisture. Do not store in the bathroom. Dispose of any unused medication when the expiration date has passed.

Warning: Before taking the drug you need to consult your doctor. The information contained in this article is not intended to cover all possible precautions, drug interactions, adverse effects, directions, uses, allergic reactions or warnings.

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