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Last updated on November 21st, 2021

Generic name: Granisetron

Brand name: Kytril

Uses for Kytril:

Kytril is a serotonin 5-HT3 receptor antagonist used as an antiemetic. Kytril is prescribed to prevent nausea and vomiting due to cancer treatment (chemotherapy) and radiation therapy. It works by blocking one of the body’s chemicals (serotonin) that causes vomiting. Your doctor may prescribe this remedy for other purposes. Contact your physician if you need to learn more information about this drug.

Don’t stop treatment with Kytril earlier than it was prescribed by your doctor even if you notice improvements of your condition. Stopping the medication too early may worsen your condition. Be careful about doing dangerous tasks, driving, operating machinery or climbing until you are aware how this drug affects you. Don’t drink alcohol.

FDA pregnancy category B. Inform your physician if you are pregnant, breast-feeding or plan to become pregnant during treatment. Your condition will be monitored after taking this remedy. Ask your doctor for more details.

What symptoms or conditions should I report to a doctor before I take this medicine?

It is important to report to a doctor if you have or had the following conditions:

  • a heart rhythm disorder
  • a personal or family history of Long QT syndrome
  • liver disease
  • an unusual or allergic reaction to Kytril, other medicines, preservatives, dyes or foods
  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood)

How to take this medicament:

Note: This remedy was prescribed to you only. Do not share this medicament with others. Follow strictly your doctor’s prescription. Do not take more or longer than your doctor recommended.

Kytril should be taken orally with some water. Doctors usually recommend taking it 1 hour before chemotherapy. Take the doses at regular intervals. Consult your pediatrician if this medication can be taken by children. Particular instructions may be needed.


Taking any medicine in large doses you can have serious consequences for your health. If you feel an overdose, contact your health care professional instantly.

In large doses, this remedy may cause headache.

What should be done if I missed the dose?

In case you forgot to take the dose, take it at your earliest opportunity. Never double your dose if it is almost time for your next dose. Take only one dose at once.

Interactions may occur with:

  •     ketoconazole
  •     phenobarbital

This list of interactions may be not complete. Provide your medical practitioners entire list of medicines, herbs, dietary supplements or non-prescription drugs you take. Moreover tell them whether you drink alcohol, use illegal drugs or smoke. Particular items may interact with your drug.

Side effects:

Contact your doctor immediately if you notice any of the following

Serious side effects:

  •     allergic reactions like difficulty breathing, itching or hives, skin rash, swelling of the tongue, lips or face
  •     irregular heartbeats
  •     unusual weakness
  •      flu symptoms, body aches, fever
  •     easy bleeding or bruising

Less serious side effects:

  • dizziness, headache
  • constipation, diarrhea, stomach pain
  • loss of appetite
  • insomnia

This list of side effects may be not complete, others may occur. Inform your medical practitioners about all side effects you experience.


Kytril should be stored at room temperature, between 15 and 30 degrees C (59 and 86 degrees F), in a tightly closed container. Protect from moisture, direct heat, and light. Do not store in the bathroom or near a sink. Keep Kytril out of the reach of children and away from animals.

Warning: Before taking the drug you need to consult your doctor. The information contained in this article is not intended to cover all possible precautions, drug interactions, adverse effects, directions, uses, allergic reactions or warnings.

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