Management of Asthma in Children: Chronic Asthma – Preventing Asthma Exacerbations

Medications used in children to control asthma symptoms and to prevent exacerbations include inhaled corticosteroids (ICSs), leukotriene receptor antagonists (LTRAs) (or leukotriene modifiers in the older children), long-acting beta2-agonists (LABAs), theophylline, and cromolyn. No daily medications are needed for mild…

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Leukotriene-receptor antagonists. Clinical models of asthma

Allergen-induced asthma In sensitized patients, inhalation of a specific allergen results in acute bronchoconstriction that usually subsides spontaneously within 2 hours; this phenomenon is known as the early asthmatic response. In many asthma patients, the early response resolves only to…

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Management of Asthma in Children: Treatment Considerations

Levalbuterol Versus Albuterol Sometimes children or their caregivers are intolerant of albuterol’s side effects, namely palpitations, tremors, hyperactivity, insomnia, and tachycardia. Levalbuterol (Xopenex), the (r)-enantiomer of racemic albuterol, was first introduced in 1999 and was subsequently FDA approved in 2002…

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Management of Asthma in Children: Asthma Education

Although millions of prescriptions are filled each year for asthma medications, Lozano et al demonstrated that the insured population who are prescribed controller medications exhibit inadequate control. Thus, pharmacists should intervene proactively and offer education as appropriate. Pharmacists in all…

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