Freely soluble in water soluble in alcohol. A white, odourless, crystalline powder.
Antiasthma Drugs
Chronic Asthma Management
Traditionally, asthma has been treated with oral and inhaled bronchodilators, which help control the symptoms of asthma but do nothing for the inflammation. Now, the focus is on prevention, which involves treating the underlying inflammation as well as the bronchoconstriction, and constantly monitoring breathing efficacy. It is essential that asthmatic patients understand how to manage drug therapy and side effects, monitor breathing efficiency, and deal with environmental factors that contribute to bronchoconstriction (irritants, allergens, exercise, cold air inhalation, and infection).
Levosalbutamol
A 1% solution has a pH of 4.5 to 5.5. Store in airtight containers at 20° to 25°, excursions permitted between 15° and 30°.
Accolate (zafirkulast)
Accolate is a nonsteroidal tablet for the prevention and continuous treatment of asthma in adults and children 5 years of age and older, available only by prescription. Accolate is not for use in the reversal of acute asthma attacks. Accolate bottle Much like a rocket has two stages, to reach its destination, Accolate(R) (zafirkulast) has twice-daily dosing, providing 24-hour leukotriene receptor antagonist (LTRA) coverage to help prevent asthma breakthrough.
Formoterol Fumarate
Slightly soluble in water and in isopropyl alcohol practically insoluble in acetonitrile soluble in methyl alcohol. A 0.1% solution in water has apH of 5.5 to 6.5.
Montelukast Sodium
Suspected adverse effects reported to the UK CSM after the launch of montelukast included oedema, agitation and restlessness, allergy (including anaphylaxis, angioedema, and urticaria), chest pain, tremor, dry mouth, vertigo, and arthralgia. Further suspected adverse effects included nightmares, sedation, palpitations, and increased sweating.
SINGULAIR (Montelukast Sodium) Tablets, Chewable Tablets, and Oral Granules
SINGULAIR is not a steroid and it’s not an inhaler. It’s a different kind of asthma controller.
Oxitropium Bromide
Very soluble in water sparingly soluble in alcohol freely soluble in methyl alcohol practically insoluble in dichloromethane. Oxitropium bromide is a quaternary ammonium antimuscarinic with actions similar to those of ipratropium bromide, to which it is structurally related. It is used as a bronchodilator in the treatment of reversible airways obstruction, as in asthma and chronic obstructive pulmonary disease.
Salmeterol Xinafoate
Practically insoluble in water slightly soluble in dehydrated alcohol soluble in methyl alcohol. Inhalation of salmeterol may be associated with paradoxical bronchospasm, and it should not be used in patients who are not also receiving an inhaled corticosteroid. Effects on the cardiovascular system.
Terbutaline Sulfate
Freely soluble in water slightly soluble in alcohol. A white to grey-white crystalline powder odourless or has a faint odour of acetic acid. Soluble in water and in 0.1N hydrochloric acid insoluble in chloroform slightly soluble in methyl alcohol.
Cetirizine Hydrochloride
Freely soluble in water practically insoluble in acetone and in dichloromethane. A 5% solution in water has a pH of 1.2 to 1.8.
Terfenadine
Very slightly soluble in water and in dilute hydrochloric acid freely soluble in dichlorometh-ane soluble in methyl alcohol. As for the non-sedating antihistamines in general.
Salbutamol
Sparingly soluble in water soluble in alcohol. Sparingly soluble in water soluble in alcohol.
Omalizumab
Injection site reactions are common with the use of omalizumab. Other adverse effects that have been reported include generalised pain, fatigue, arthralgia, dizziness, earache, gastrointestinal disturbances, headache, and alopecia. An increased incidence of parasitic infection has been reported in patients at high risk for helminthic infections.
Fenoterol
Soluble in water and in alcohol. A 4% solution in water has a pH of 4.2 to 5.2.
Loratadine
Practically insoluble in water freely soluble in acetone and in methyl alcohol. Insoluble in water freely soluble in acetone, in chloroform, in methyl alcohol, and in toluene.
Orciprenaline Sulfate
A white, slightly hygroscopic, crystalline powder. Freely soluble in water slightly soluble in alcohol practically insoluble in dichloromethane.
Astemizole
Practically insoluble in water soluble in alcohol freely soluble in dichloromethane and in methyl alcohol. As for the non-sedating antihistamines in general.