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Methaqualone

Drug Approvals

(British Approved Name, US Adopted Name, rINN)

INNs in other languages (French, Latin, and Spanish):

Synonyms: CI-705; CN-38703; Metacualona; Metakvalon; Metakvalonas; Metakvaloni; Methachalonum; Methakvalon; Methaqualonum; QZ-2; R-148; TR-495
BAN: Methaqualone
USAN: Methaqualone
INN: Methaqualone [rINN (en)]
INN: Metacualona [rINN (es)]
INN: Méthaqualone [rINN (fr)]
INN: Methaqualonum [rINN (la)]
INN: Метахалон [rINN (ru)]
Chemical name: 2-Methyl-3-o-tolylquinazolin-4-(3H)-one
Molecular formula: C16H14N2O =250.3
CAS: 72-44-6 (methaqualone); 340-56-7 (methaqualone hydrochloride)
ATC code: N05CM01

Note. The following terms have been used as ‘street names’ or slang names for various forms of methaqualone: 300’s; 714; 714s; Bandits; Beiruts; Blou Bulle; Blue Balls; Bluebulls; Disco biscuits; Down and dirtys; Drunfos; Drunken Monkey; Ewings; Flamingos; Flowers; Four-strokes; Fuckers; Genuines; Germans; Golfsticks; Gorilla Biscuits; Humbles; Joe Fridays; Knoppies; Lemmon 714; Lemons; Lennons; Lewds; Lizards; Loss-of-memory; Love drug; Lovers; Ludes; Luds; Lula; Magwheels; Pressouts; Pupumala; Q; Qua; Quaa; Quaalude; Quaaludes; Quaas; Quack; Quad; Quads; Quas; Seven fourteens;Shiny Tops; Soaper; Sopor; Sopors; Sporos; Strawberries; SuperSopors; Supers; Supper; Three hundreds; Vitamin Q; WagonWheels; Wallbangers; Whore pills.

Pharmacopoeias. In Europe.

European Pharmacopoeia, 6th ed. (Methaqualone). A white or almost white, crystalline powder. Very slightly soluble in water soluble in alcohol dissolves in dilute sulfuric acid. Protect from light.

Methaqualone300

Profile

Methaqualone is a quinazoline derivative with hypnotic and sedative properties. It has been given orally in the short-term management of insomnia but the use of methaqualone for this purpose is no longer considered appropriate. It has also been given with diphenhydramine for an enhanced effect. Methaqualone has been withdrawn from the market in many countries because of problems with abuse. Adverse effects and symptoms of overdosage are similar to those of barbiturates (see Amobarbital) although cardiac and respiratory depression reportedly occur less frequently.

Abuse. Although oral abuse of methaqualone has greatly declined in developed countries after the widespread withdrawal of the tablets, smoking of (usually illicitly manufactured) methaqualone, generally in combination with cannabis and tobacco, is a major public health problem in South Africa, and some other parts of Africa and India. Although diazepam has been used to manage dependence, controlled studies to inform the management of the condition are lacking.

Preparations – Multi-ingredient

Switzerland: Toquilone compositum

 

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