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Ponstel (Mefenamic Acid)

Last updated on November 14th, 2021

Generic name: Mefenamic Acid

Brand names: Ponstel

General Information

Ponstel belongs to a nonsteroidal anti-inflammatory medications. It is recommended to take in moderate pain as well as menstrual pain.

You need to visit your doctor often if you take Ponstel on a regular basis. Be aware: internal bleeding or ulcers can occur without prior symptoms.

How do I take this medicine?

Note: This remedy was prescribed to you only. Do not share this medicament with others.

Take it with food and drink the glass of water in order to avoid problems with stomach. Follow exact prescription of your healthcare provider or pharmacist.

What should be done if I miss a dose?

In case you take this pill regularly, take missed dose as soon as it is possible. Don’t double dose if it is almost time for your next dose. Take only one dose at once.

How should I store this medication?

Store this pill away from children, animals, heat, moisture and light.

Possible side effects.

vomiting, nausea, diarrhea, abdominal pain, intestinal upset, stomach upset.

You should not take this medication if you have allergy to any component of it, or if you had hives caused by aspirin, hay fever, asthma attacks caused by other nonsteroidal anti-inflammatory drugs.

Contact your doctor if you experience any of the side effects. Also inform your healthcare provider or pharmacist about any drug reactions you have experienced.

Avoid taking this drug if you have frequently recurring inflammation of your stomach,ulcerations, intestines or kidney disease.

Warnings about this drug!

You need to use this remedy extremely carefully if you’ve had stomach bleeding or ulcers. Inform your physician in case you develop a diarrhea, rash or other problems with stomach. If you suffer from dehydration, you are an older adult, if you have or had heart failure, liver or kidney disease, if you take drugs such as diuretics or ACE inhibitors, this pill may negativel affect your kidneys and should be taken with extreme caution.

This drug may also cause liver damage. Contact your doctor if you experience itching, fatigue, nausea, upper abdominal pain, yellowing of the eyes and skin, flu-like symptoms. This pill can also aggravate heart failure, high blood pressure, asthma . Use it carefully if you smoke.

Below is the list of possible drugs and food interactions:

It is of highest importance to know the interactions of the remedy you take:

  • Lithium
  • Aspirin
  • Diuretics
  • Alcohol
  • Methotrexate
  • Trimethoprim
  • ACE inhibitors (drugs for high blood pressure)
  • Blood-thinning medications
  • Fluconazole
  • Lovastatin
  • Steroids such as prednisone and hydrocortisone
  • ponstel-500mg

Pregnancy and Lactation

Thre is not enough information about how this remedy effects foetus. Inform your doctor if you are planning to become pregnant or if you are pregnant. This drug may appear in breast milk and could affect a baby.If this pill is essential to your health, your physician may recommend you to stop breastfeeding until your treatment is finished.

Ponstel recommended dosage:

Adults and children older 14:

Moderate Pain

It is recommended to begin with 500 milligrams, followed by 250 milligrams every six hours, if needed, during 7 days.

Menstrual Pain

It is recommended to begin with 500 milligrams, followed by 250 milligrams every 6 hours during two or three days.


There is not enough information about using this remedy by children under 14.


If you consider you are overdosed, seek immediate medical attention.

Symptoms of Ponstel overdose:

abdominal pain, lack of energy, vomiting, stomach pain, nausea, drowsiness. In severe cases patients may experience coma and breathing problems.

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